3-Phenylpropenoic acid 2-methyl-2-propenyl ester

Base Information

• Chemical Name: 3-Phenylpropenoic acid 2-methyl-2-propenyl ester
• CAS No.: 54889-46-2
• Molecular Formula: C13H14O2
• Molecular Weight: 202.24900
• Hs Code.: 2916399090
• Mol file: 54889-46-2.mol

Synonyms:trans-Zimtsaeure-methallylester;2-Propenoic acid,3-phenyl-,2-methyl-2-propenyl ester;trans-cinnamic acid methallyl ester;

Chemical Property of 3-Phenylpropenoic acid 2-methyl-2-propenyl ester

Chemical Property:

• Boiling Point: 145-153 °C(Press: 8 Torr)
• PSA: 26.30000
• Density: 1.038±0.06 g/cm3(Predicted)
• LogP: 2.81910

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Phenylpropenoic acid 2-methyl-2-propenyl ester

There total 1 articles about 3-Phenylpropenoic acid 2-methyl-2-propenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(E)-3-phenylacrylic acid (140-10-3) + 2-methylprop-1-en-1-ol (56640-70-1) → 2-methylallyl cinnamate (54889-46-2)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/anie.201904411

Reference yield: 67.0%

2-methylallyl cinnamate (54889-46-2) → 2-benzyl-4-methylpent-4-enoic acid (37092-73-2)

Guidance literature:

With 2-(benzyloxy)-1,3-di-tert-butyl-2,3-dihydro-1H-1,3,2-diazaphosphole; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; In tetrahydrofuran; at 23 ℃; for 4h; Glovebox; Sealed tube;

DOI:10.1002/anie.201904411

upstream raw materials:

(E)-3-phenylacrylic acid

2-methylprop-1-en-1-ol

Downstream raw materials:

2-benzyl-4-methylpent-4-enoic acid

Refernces