N-Butylisomaleimide

Base Information

• Chemical Name: N-Butylisomaleimide
• CAS No.: 27396-39-0
• Molecular Formula: C8H11 N O2
• Molecular Weight: 153.181
• Hs Code.: 2932209090
• Mol file: 27396-39-0.mol

Synonyms:N-Butylisomaleimide

Chemical Property of N-Butylisomaleimide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 331.2°Cat760mmHg
• Flash Point: 176.5°C
• PSA: 38.66000
• Density: 1.09g/cm³
• LogP: 1.29640
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 153.078978594
• Heavy Atom Count: 11
• Complexity: 196

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC=NC1C=CC(=O)O1
• Isomeric SMILES: CCC/C=N\C1C=CC(=O)O1

Technology Process of N-Butylisomaleimide

There total 2 articles about N-Butylisomaleimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-butylmaleamic acid (45019-30-5,4733-76-0) → maleic acid N-butylisoimide (27396-39-0)

Guidance literature:

With 4-methyl-morpholine; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; In ethyl acetate; at -20 - 4 ℃;

DOI:10.1080/00397911.2012.727060

Reference yield:

→ maleic acid N-butylisoimide (27396-39-0)

Guidance literature:

Ethylchlorformiat 1)Triethylammonium-N-butylmaleamat, CH2Cl2, 0-5grad, 1 Std. 2)Befreiung v.ausgeschiedenem NEt3*HCl;

DOI:10.1021/jo01060a003

Reference yield:

dimethylketene (598-26-5) + maleic acid N-butylisoimide (27396-39-0) → 1-butyl-3,3-dimethyl-5-oxa-1-aza-spiro[3.4]oct-7-ene-2,6-dione (72291-68-0)

Guidance literature:

In ethyl acetate;

DOI:10.1002/hlca.19790620625

upstream raw materials:

N-butylmaleamic acid

Downstream raw materials:

1-butyl-3,3-dimethyl-5-oxa-1-aza-spiro[3.4]oct-7-ene-2,6-dione

1-butyl-3,3-diphenyl-5-oxa-1-aza-spiro[3.4]oct-7-ene-2,6-dione

(Z)-Butyl methyl maleamate

Refernces