2-Propen-1-one, 3-(2-bromophenyl)-1-(2-hydroxyphenyl)-

Base Information

Chemical Name:2-Propen-1-one, 3-(2-bromophenyl)-1-(2-hydroxyphenyl)-
CAS No.:55370-65-5
Molecular Formula:C₁₅H₁₁BrO₂
Molecular Weight:303.155
Hs Code.:
European Community (EC) Number:653-464-7
Nikkaji Number:J1.363.749K
ChEMBL ID:CHEMBL412780

Synonyms:2-Propen-1-one, 3-(2-bromophenyl)-1-(2-hydroxyphenyl)-;55370-65-5;2'-Hydroxy-2-bromochalcone;CHEMBL412780;SCHEMBL8106958;(E)-3-(2-bromophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one;AKOS024334203;CCG-262243;1-(2-Hydroxyphenyl)-3-(2-bromophenyl)-2-propene-1-one;(2E)-3-(2-bromophenyl)-1-(2-hydroxyphenyl)-2-propen-1-one

Suppliers and Price of 2-Propen-1-one, 3-(2-bromophenyl)-1-(2-hydroxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Propen-1-one, 3-(2-bromophenyl)-1-(2-hydroxyphenyl)-

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:301.99424
Heavy Atom Count:18
Complexity:314

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C=CC(=O)C2=CC=CC=C2O)Br
Isomeric SMILES:C1=CC=C(C(=C1)/C=C/C(=O)C2=CC=CC=C2O)Br

Technology Process of 2-Propen-1-one, 3-(2-bromophenyl)-1-(2-hydroxyphenyl)-

There total 4 articles about 2-Propen-1-one, 3-(2-bromophenyl)-1-(2-hydroxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 6630-33-7
ortho-bromobenzaldehyde

: 55370-65-5,145626-25-1
(E)-3-(2-bromophenyl)-1-(2'-hydroxyphenyl)prop-2-en-1-one

Guidance literature:: o-hydroxyacetophenone; With potassium hydroxide; In ethanol; at 0 ℃; for 0.166667h;

ortho-bromobenzaldehyde; In ethanol; at 0 - 20 ℃; for 15h;
DOI:10.3390/molecules23030597

Reference yield:

: 3-(2-bromo-phenyl)-3-hydroxy-1-(2-hydroxy-phenyl)-propan-1-one

: 55370-65-5,145626-25-1
(E)-3-(2-bromophenyl)-1-(2'-hydroxyphenyl)prop-2-en-1-one

Guidance literature:: With oxonium; at 20 ℃;
DOI:10.1016/S0960-894X(00)00361-9

Reference yield:

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 55370-65-5,145626-25-1
(E)-3-(2-bromophenyl)-1-(2'-hydroxyphenyl)prop-2-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 10 percent NaOH / ethanol

2: H₃O⁽¹⁺⁾ / 20 °C

With sodium hydroxide; oxonium; In ethanol; 1: Condensation / 2: Dehydration;
DOI:10.1016/S0960-894X(00)00361-9