3,6-Dibromopyrazolo[1,5-a]pyrimidine

Base Information

Chemical Name:3,6-Dibromopyrazolo[1,5-a]pyrimidine
CAS No.:55405-68-0
Molecular Formula:C₆H₃Br₂N₃
Molecular Weight:276.918
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50480292
Wikidata:Q82314978
Mol file:55405-68-0.mol

Synonyms:3,6-Dibromopyrazolo[1,5-a]pyrimidine;55405-68-0;Pyrazolo[1,5-a]pyrimidine, 3,6-dibromo-;3,6-DIBROMO-PYRAZOLO[1,5-A]PYRIMIDINE;SCHEMBL3754835;DTXSID50480292;UTYZRARNCOWBRK-UHFFFAOYSA-N;AMY26063;MFCD12923112;AKOS016006057;AS-43201;CS-0080432;FT-0742135;EN300-1130104;A870201;Z1269242411

Suppliers and Price of 3,6-Dibromopyrazolo[1,5-a]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3,6-Dibromopyrazolo[1,5-a]pyrimidine 95+%
5g
$ 950.00

Crysdot
3,6-Dibromopyrazolo[1,5-a]pyrimidine 95+%
1g
$ 270.00

Crysdot
3,6-Dibromopyrazolo[1,5-a]pyrimidine 95+%
250mg
$ 160.00

Chemenu
3,6-dibromopyrazolo[1,5-a]pyrimidine 95+%
1g
$ 1080.00

Chemenu
3,6-dibromopyrazolo[1,5-a]pyrimidine 95+%
5g
$ 3007.00

Chemcia Scientific
3,6-Dibromo-pyrazolo[1,5-a]pyrimidine ＞97%
1 G
$ 230.00

American Custom Chemicals Corporation
3,6-DIBROMOPYRAZOLO[1,5-A]PYRIMIDINE 95.00%
5MG
$ 503.86

AK Scientific
3,6-Dibromopyrazolo[1,5-a]pyrimidine
5g
$ 1131.00

AK Scientific
3,6-Dibromopyrazolo[1,5-a]pyrimidine
1g
$ 357.00

Total 12 raw suppliers

Chemical Property of 3,6-Dibromopyrazolo[1,5-a]pyrimidine

Chemical Property:

PSA：30.19000
Density:2.36g/cm3
LogP:2.25430
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:276.86732
Heavy Atom Count:11
Complexity:155

Purity/Quality:

97% ^*data from raw suppliers

3,6-Dibromopyrazolo[1,5-a]pyrimidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=NC2=C(C=NN21)Br)Br

Technology Process of 3,6-Dibromopyrazolo[1,5-a]pyrimidine

There total 1 articles about 3,6-Dibromopyrazolo[1,5-a]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55405-68-0
3,6-dibromopyrazolo[1,5-a]pyrimidine

Guidance literature:: 1, Br2, EtOH, H2O, Bromierung;
DOI:10.1139/v75-016

Reference yield:

: 55405-68-0
3,6-dibromopyrazolo[1,5-a]pyrimidine

: 1314893-38-3
N-[(1R,6R)-6-amino-2,2-difluorocyclohexyl]-4-[6-(difluoromethoxy)pyrazolo[1,5-a]pyrimidin-3-yl]-5-methylthiophene-2-carboxamide

Guidance literature:: Multi-step reaction with 6 steps

1.1: potassium hydroxide / methanol / 64 h / 65 °C

2.1: potassium carbonate / water; N,N-dimethyl acetamide / 16 h / 100 °C

3.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide; water / 16 h / 85 °C / Inert atmosphere

4.1: potassium hydroxide; water / tetrahydrofuran; methanol / 16 h / 40 °C

5.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 20 °C

5.2: 16 h / 20 °C

6.1: trifluoroacetic acid / dichloromethane / 16 h / 20 °C

With water; sodium carbonate; potassium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; trifluoroacetic acid; potassium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl acetamide; water; N,N-dimethyl-formamide;

Reference yield:

: 55405-68-0
3,6-dibromopyrazolo[1,5-a]pyrimidine

: 1314894-25-1
tert-butyl [(1R,2R)-2-[({4-[6-(difluoromethoxy)pyrazolo[1,5-a]pyrimidin-3-yl]-5-ethylthiophen-2-yl}carbonyl)amino]-3,3-difluorocyclohexyl]carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydroxide / methanol / 64 h / 65 °C

2: potassium carbonate / water; N,N-dimethyl acetamide / 16 h / 100 °C

3: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide; water / 16 h / 85 °C / Inert atmosphere

With sodium carbonate; potassium carbonate; potassium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; N,N-dimethyl acetamide; water; N,N-dimethyl-formamide;