2-Tolyl-hydrazonomalononitrile

Base Information

• Chemical Name: 2-Tolyl-hydrazonomalononitrile
• CAS No.: 55653-08-2
• Molecular Formula: C10H8N4
• Molecular Weight: 184.2
• DSSTox Substance ID: DTXSID40876221
• Nikkaji Number: J1.232.154F
• Mol file: 55653-08-2.mol

Synonyms:2-tolyl-hydrazonomalononitrile;55653-08-2;SCHEMBL922606;DTXSID40876221;GARUNYYLNCCBTO-UHFFFAOYSA-N;2-(o-tolylhydrazono)-malononitrile;AKOS003611188;CARBONYLCYANIDE2METHYLPHENYLHYDRAZONE

Chemical Property of 2-Tolyl-hydrazonomalononitrile

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 184.074896272
• Heavy Atom Count: 14
• Complexity: 296

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=CC=C1NN=C(C#N)C#N

Technology Process of 2-Tolyl-hydrazonomalononitrile

There total 6 articles about 2-Tolyl-hydrazonomalononitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

o-toluene-diazonium chloride (2028-34-4) + malononitrile (109-77-3) → 2-[2-(2-methylphenyl)hydrazono]malononitrile (55653-08-2)

Guidance literature:

With sodium acetate; In ethanol; water; at 0 - 5 ℃;

DOI:10.1007/PL00010201

Reference yield: 93.0%

2-methylphenyl diazonium tetrafluoroborate (2093-46-1) + malononitrile (109-77-3) → 2-[2-(2-methylphenyl)hydrazono]malononitrile (55653-08-2)

Guidance literature:

With sodium acetate; silica gel; In neat (no solvent); at 20 ℃; for 0.333333h; Milling;

DOI:10.2174/1570178611999140404111411

Reference yield: 82.0%

o-toluidine (95-53-4) + malononitrile (109-77-3) → 2-[2-(2-methylphenyl)hydrazono]malononitrile (55653-08-2)

Guidance literature:

o-toluidine; With sodium nitrite; for 0.0833333h;

In water; for 0.166667h;

malononitrile; 2-methylphenyl diazonium silica sulfate nanocomposite; With potassium carbonate; In water; at 20 ℃; for 0.166667h;

DOI:10.1016/j.dyepig.2021.109544

upstream raw materials:

o-toluene-diazonium chloride

malononitrile

o-toluidine

2-methylphenyl diazonium tetrafluoroborate

Downstream raw materials:

4-(o-methylphenylazo)-3,5-diamino-1H-pyrazole

(4-amino-8-methyl-cinnolin-3-yl)-p-tolyl-methanone

(4-acetamido-8-methyl-cinnolin-3-yl)-p-tolyl-methanone

2-amino-5-methyl-3-o-tolylazo-6H-pyrazolo[1,5-a]pyrimidin-7-one