2-(4-Methylphenoxy)benzaldehyde

Base Information

• Chemical Name: 2-(4-Methylphenoxy)benzaldehyde
• CAS No.: 19434-35-6
• Molecular Formula: C14H12O2
• Molecular Weight: 212.248
• Hs Code.: 2912499000
• DSSTox Substance ID: DTXSID70363058
• Nikkaji Number: J3.114.876F
• Wikidata: Q72494556
• Mol file: 19434-35-6.mol

Synonyms:19434-35-6;2-(4-methylphenoxy)benzaldehyde;2-(p-Tolyloxy)benzaldehyde;2-(4-methylphenoxy)benzenecarbaldehyde;MFCD01568738;2-p-Tolyloxy-benzaldehyde;SCHEMBL1200720;DTXSID70363058;2-(4-methylphenoxy)-benzaldehyde;AKOS000260214;AC-26266;CS-0316371;FT-0637848;F79360;11N-093;A813723;2-(4-methylphenoxy)benzenecarbaldehyde, AldrichCPR;J-506572

Chemical Property of 2-(4-Methylphenoxy)benzaldehyde

Chemical Property:

• Vapor Pressure: 0.000408mmHg at 25°C
• Melting Point: 52-54°
• Refractive Index: 1.599
• Boiling Point: 316.5 °C at 760 mmHg
• Flash Point: 136.2 °C
• PSA: 26.30000
• Density: 1.129 g/cm³
• LogP: 3.59980
• Sensitive.: Air Sensitive
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 212.083729621
• Heavy Atom Count: 16
• Complexity: 219

Purity/Quality:

99% ^*data from raw suppliers

2-(4-methylphenoxy)benzenecarbaldehyde ^*data from reagent suppliers

Safty Information:

• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)OC2=CC=CC=C2C=O

Technology Process of 2-(4-Methylphenoxy)benzaldehyde

There total 7 articles about 2-(4-Methylphenoxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

p-cresol (106-44-5) + 2-Fluorobenzaldehyde (446-52-6) → 2-(4'-methylphenoxy)benzaldehyde (19434-35-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl acetamide; at 170 ℃; for 4h;

DOI:10.1021/ol4000857

Reference yield: 90.0%

p-cresol (106-44-5) + 2-nitro-benzaldehyde (552-89-6) → 2-(4'-methylphenoxy)benzaldehyde (19434-35-6)

Guidance literature:

With copper(II) acetate monohydrate; caesium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 4h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.tet.2012.08.032

Reference yield: 55.0%

p-cresol (106-44-5) + 2-chloro-benzaldehyde (89-98-5) → 2-(4'-methylphenoxy)benzaldehyde (19434-35-6)

Guidance literature:

With copper(I) oxide; caesium carbonate; In N,N-dimethyl-formamide; at 140 ℃; for 24h; Inert atmosphere; Green chemistry;

DOI:10.1016/j.tetlet.2013.09.079

upstream raw materials:

4-tolyl iodide

salicylaldehyde

para-bromotoluene

p-cresol

Downstream raw materials:

N'-{(1E)-[2-(4-methylphenoxy)phenyl]methylene}-2-phenylacetohydrazide

2-methyl-9H-xanthene

p-tolyl 2-hydroxybenzoate

methyl 2-(4-methylphenoxy)benzoate