4-(4-Chlorophenyl)-1H-1,2,3-triazole

Base Information

• Chemical Name: 4-(4-Chlorophenyl)-1H-1,2,3-triazole
• CAS No.: 5604-31-9
• Molecular Formula: C8H6ClN3
• Molecular Weight: 179.609
• Mol file: 5604-31-9.mol

Synonyms:4-(4-Chloro-phenyl)-1H-[1,2,3]triazole;4-p-Chlorphenyl-1,2,3-triazol;1-H-4-(p-Chlorphenyl)-1,2,3-triazol;4-(p-Chlor-phenyl)-1H-1,2,3-triazol;4-(p-Chlorphenyl)-1H-1,2,3-triazol;

Chemical Property of 4-(4-Chlorophenyl)-1H-1,2,3-triazole

Chemical Property:

• PSA: 41.57000
• LogP: 2.12510

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(4-Chlorophenyl)-1H-1,2,3-triazole

There total 25 articles about 4-(4-Chlorophenyl)-1H-1,2,3-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-chloro-4-(2-nitrovinyl)benzene (706-07-0,5153-70-8) → 4-(4-chlorophenyl)-1H-1,2,3-triazole (5604-31-9)

Guidance literature:

With sodium azide; copper(II) ferrite; In dimethyl sulfoxide; at 120 ℃; for 0.0333333h; Microwave irradiation;

DOI:10.1016/j.tetlet.2018.03.032

Reference yield: 95.0%

nitromethane (75-52-5) + 4-chlorobenzaldehyde (104-88-1) → 4-(4-chlorophenyl)-1H-1,2,3-triazole (5604-31-9)

Guidance literature:

With sodium azide; copper(II) ferrite; In dimethyl sulfoxide; at 120 ℃; for 0.0833333h; Solvent; Reagent/catalyst; Microwave irradiation;

DOI:10.1016/j.tetlet.2018.03.032

Reference yield: 95.0%

1-chloro-4-(2-nitrovinyl)benzene (706-07-0,5153-70-8) → 5-(4-chlorophenyl)-1H-1,2,3-triazole (5604-31-9)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 60 ℃; for 1h; Sealed tube; Green chemistry;

DOI:10.1080/00397911.2018.1510007

upstream raw materials:

4-chlorobenzoylmethylenetriphenylphosphorane

4-n-chlorophenylacetylene

nitromethane

4-chlorobenzaldehyde