Vinetorin

Base Information

Chemical Name:Vinetorin
CAS No.:23460-01-7
Molecular Formula:C₁₅H₁₁ClO₅
Molecular Weight:306.702
Hs Code.:2932999099
NSC Number:319946
DSSTox Substance ID:DTXSID00419512
Nikkaji Number:J1.256.377I
Wikidata:Q77517041
Metabolomics Workbench ID:105553
Mol file:23460-01-7.mol

Synonyms:vinetorin;23460-01-7;NSC319946;XANTHONE 2;DTXSID00419512;CHEBI:144246;NSC-319946;5-Chloro-1,6-dihydroxy-3-methoxy-8-methylxanthone;4-CHLORO-3,8-DIHYDROXY-6-METHOXY-1-METHYL-9H-XANTHEN-9-ONE

Suppliers and Price of Vinetorin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Vinetorin

Chemical Property:

Vapor Pressure:8.33E-13mmHg at 25°C
Melting Point:254-255 °C(Solv: ethyl acetate (141-78-6))
Boiling Point:552.3°C at 760 mmHg
PKA:5.69±0.20(Predicted)
Flash Point:287.8°C
PSA：79.90000
Density:1.513g/cm³
LogP:3.32780
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:306.0295011
Heavy Atom Count:21
Complexity:417

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C2=C1C(=O)C3=C(C=C(C=C3O2)OC)O)Cl)O

Technology Process of Vinetorin

There total 9 articles about Vinetorin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 621-23-8
1,2,3-trimethoxybenzene

: 23460-01-7
5-chloro-1,6-dihydroxy-3-methoxy-8-methylxanthone

Guidance literature:: Multi-step reaction with 5 steps

1: 2.7 g / trifluoroacetic anhydride / CH₂Cl₂ / 0.17 h / 0 °C

2: hydrogen, aq. hydrochloric acid / palladized charcoal / ethyl acetate

3: 850 mg / potassium hydroxide / ethanol / 1.5 h / Heating

4: pyridine / 90 °C

5: 336 mg / boron trichloride / CH₂Cl₂ / 1 h / 0 °C

With pyridine; hydrogenchloride; potassium hydroxide; hydrogen; boron trichloride; trifluoroacetic anhydride; palladium on activated charcoal; In ethanol; dichloromethane; ethyl acetate;

Reference yield:

: 74212-72-9
Acetic acid 4-chloro-6,8-dimethoxy-1-methyl-9-oxo-9H-xanthen-3-yl ester

: 23460-01-7
5-chloro-1,6-dihydroxy-3-methoxy-8-methylxanthone

Guidance literature:: With boron trichloride; In dichloromethane; at 0 ℃; for 1h;

Reference yield:

: 38103-07-0
methyl 3-chloro-2,4-dihydroxy-6-methylbenzoate

: 23460-01-7
5-chloro-1,6-dihydroxy-3-methoxy-8-methylxanthone

Guidance literature:: Multi-step reaction with 7 steps

1: 10.4 g / potassium carbonate / dimethylformamide / 15 h

2: 9.7 g / potassium hydroxide, water / dimethylsulfoxide / 6 h / Heating

3: 2.7 g / trifluoroacetic anhydride / CH₂Cl₂ / 0.17 h / 0 °C

4: hydrogen, aq. hydrochloric acid / palladized charcoal / ethyl acetate

5: 850 mg / potassium hydroxide / ethanol / 1.5 h / Heating

6: pyridine / 90 °C

7: 336 mg / boron trichloride / CH₂Cl₂ / 1 h / 0 °C

With pyridine; hydrogenchloride; potassium hydroxide; water; hydrogen; boron trichloride; potassium carbonate; trifluoroacetic anhydride; palladium on activated charcoal; In ethanol; dichloromethane; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;