Acetyl chloride, [[(4-methylphenyl)sulfonyl]amino]-

Base Information

Chemical Name:Acetyl chloride, [[(4-methylphenyl)sulfonyl]amino]-
CAS No.:56218-62-3
Molecular Formula:C9H10ClNO3S
Molecular Weight:247.702
Hs Code.:
DSSTox Substance ID:DTXSID00456982
Nikkaji Number:J1.635.795B
Wikidata:Q82279637

Synonyms:56218-62-3;Acetyl chloride, [[(4-methylphenyl)sulfonyl]amino]-;N-tosyl-glycyl chloride;SCHEMBL1997197;DTXSID00456982;N-(2-Chloro-2-oxoethyl)-4-methylbenzenesulfonamide

Suppliers and Price of Acetyl chloride, [[(4-methylphenyl)sulfonyl]amino]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetyl chloride, [[(4-methylphenyl)sulfonyl]amino]-

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:247.0069920
Heavy Atom Count:15
Complexity:315

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)Cl

Technology Process of Acetyl chloride, [[(4-methylphenyl)sulfonyl]amino]-

There total 3 articles about Acetyl chloride, [[(4-methylphenyl)sulfonyl]amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1080-44-0
N-Tosylglycine

: 56218-62-3
2-(4-methylphenylsulfonamido)acetyl chloride

Guidance literature:: With thionyl chloride; for 1.5h; Heating / reflux;

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 56218-62-3
2-(4-methylphenylsulfonamido)acetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydrogencarbonate / water / 0.33 h / 0 °C / Inert atmosphere

1.2: 16 h / Inert atmosphere; Sealed tube

2.1: thionyl chloride / tetrahydrofuran / 1 h / 0 - 23 °C / Inert atmosphere; Sealed tube

With thionyl chloride; sodium hydrogencarbonate; In tetrahydrofuran; water;
DOI:10.1021/acs.orglett.5b03708