N-Acetyl-L-tyrosyl-L-alanine

Base Information

Chemical Name:N-Acetyl-L-tyrosyl-L-alanine
CAS No.:56272-47-0
Molecular Formula:C₁₄H₁₈N₂O₅
Molecular Weight:294.307
Hs Code.:
DSSTox Substance ID:DTXSID20569447
Nikkaji Number:J130.735E
Wikidata:Q82456601

Synonyms:N-Acetyl-L-tyrosyl-L-alanine;56272-47-0;N-Acetyltyrosyl-alanine;SCHEMBL9292479;DTXSID20569447;OESFJKBHQUNLDE-UFBFGSQYSA-N

Suppliers and Price of N-Acetyl-L-tyrosyl-L-alanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-Acetyl-L-tyrosyl-L-alanine

Chemical Property:

PSA：122.71000
LogP:1.70930
XLogP3:-0.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:294.12157168
Heavy Atom Count:21
Complexity:391

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C
Isomeric SMILES:C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C

Technology Process of N-Acetyl-L-tyrosyl-L-alanine

There total 6 articles about N-Acetyl-L-tyrosyl-L-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 80630-69-9
N,O-diacetyltyrosyl-alanine methyl ester

: 56272-47-0
N-acetyltyrosyl-alanine

Guidance literature:: With sodium hydroxide; In methanol; for 1h;
DOI:10.1135/cccc19920179

Reference yield:

: 17355-23-6
N-acetyl-O-acetyl-L-tyrosine

: 56272-47-0
N-acetyltyrosyl-alanine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) ethyl chloroformate, N-ethylpiperidine / 1.) THF, -15 deg C, 15 min, 2.) THF, from 0 deg C to RT, 14 h

2: 2M NaOH / methanol / 1 h

With 1-ethyl-piperidine; sodium hydroxide; chloroformic acid ethyl ester; In methanol;
DOI:10.1135/cccc19920179

Reference yield:

: 3978-80-1
Boc-Tyr-OH

: 56272-47-0
N-acetyltyrosyl-alanine

Guidance literature:: Multi-step reaction with 3 steps

1: dicyclohexyl-carbodiimide; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

2: water / diethyl ether / Cooling

3: N-ethyl-N,N-diisopropylamine / dichloromethane / 4 h

With water; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In diethyl ether; dichloromethane;
DOI:10.1002/anie.201207730