L-Glutamic acid, N-(4-formylbenzoyl)-, diethyl ester

Base Information

Chemical Name:L-Glutamic acid, N-(4-formylbenzoyl)-, diethyl ester
CAS No.:56277-36-2
Molecular Formula:C17H21NO6
Molecular Weight:335.357
Hs Code.:
DSSTox Substance ID:DTXSID80537647
Wikidata:Q82412708

Synonyms:56277-36-2;L-Glutamic acid, N-(4-formylbenzoyl)-, diethyl ester;diethyl (2S)-2-[(4-formylbenzoyl)amino]pentanedioate;SCHEMBL10965936;DTXSID80537647;Diethyl N-(4-formylbenzoyl)-L-glutamate

Suppliers and Price of L-Glutamic acid, N-(4-formylbenzoyl)-, diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of L-Glutamic acid, N-(4-formylbenzoyl)-, diethyl ester

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:335.13688739
Heavy Atom Count:24
Complexity:442

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CCC(C(=O)OCC)NC(=O)C1=CC=C(C=C1)C=O
Isomeric SMILES:CCOC(=O)CC[C@@H](C(=O)OCC)NC(=O)C1=CC=C(C=C1)C=O

Technology Process of L-Glutamic acid, N-(4-formylbenzoyl)-, diethyl ester

There total 4 articles about L-Glutamic acid, N-(4-formylbenzoyl)-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 1118-89-4
diethyl-L-glutamate hydrochloride

: 619-66-9
4-Carboxybenzaldehyde

: 56277-36-2
diethyl 4-formylbenzoyl-L-glutamate

Guidance literature:: With pyridine; dicyclohexyl-carbodiimide; for 168h;
DOI:10.1021/jm950786p

Reference yield:

: 220545-64-2
(E)-diethyl N-<4-<4-(5-formyl-4-methoxy-2-pivaloylaminopyrimidin-4-yl)-N-4-methoxybenzylamino>-1-butenyl>benzoyl-L-glutamate

: 56277-36-2
diethyl 4-formylbenzoyl-L-glutamate

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / NH₂OH*HCl, pyridine / ethanol / 3 h / Ambient temperature

2: 1.) NCS, 2.) Et₃N / 1.) CH₂Cl₂, room temperature, 3 h, 2.) 3 h

3: 5 mg / Mo(CO)6 / H₂O; acetonitrile / 1 h / Heating

With pyridine; N-chloro-succinimide; hexacarbonyl molybdenum; hydroxylamine hydrochloride; triethylamine; In ethanol; water; acetonitrile;
DOI:10.1016/S0040-4020(98)01060-6

Reference yield:

: (E)-diethyl N-<4-<4-(4-methoxy-5-oximinomethyl-2-pivaloylaminopyrimidin-4-yl)-N-4-methoxybenzylamino>-1-butenyl>benzoyl-L-glutamate

: 56277-36-2
diethyl 4-formylbenzoyl-L-glutamate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NCS, 2.) Et₃N / 1.) CH₂Cl₂, room temperature, 3 h, 2.) 3 h

2: 5 mg / Mo(CO)6 / H₂O; acetonitrile / 1 h / Heating

With N-chloro-succinimide; hexacarbonyl molybdenum; triethylamine; In water; acetonitrile;
DOI:10.1016/S0040-4020(98)01060-6