Technology Process of 2,5,5-Trimethyl-1,2,3,4,5,6,7,8-octahydronaphthalene-2-ethanal
There total 10 articles about 2,5,5-Trimethyl-1,2,3,4,5,6,7,8-octahydronaphthalene-2-ethanal which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
diisobutylaluminium hydride;
In
hexane; dichloromethane;
DOI:10.1039/c39940002781
- Guidance literature:
-
Multi-step reaction with 10 steps
2: 100 percent / p-ClC6H4NCO, NEt3 / benzene
3: H2, B(OMe)3 / Raney-Ni / methanol; H2O
4: D-camphor-10-sulfonic acid / CH2Cl2
5: Zn, TiCl4 / tetrahydrofuran; CH2Cl2
6: 43 percent / benzene / 48 h / 160 °C
7: 5percent Na-Hg / methanol
8: nBu4NF / tetrahydrofuran
9: 1) p-TsCl / 1) pyridine, 2) DMSO
10: 70 percent / iBu2AlH / hexane; CH2Cl2
With
sodium amalgam; Trimethyl borate; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; hydrogen; p-chlorphenylisocyanate; titanium tetrachloride; diisobutylaluminium hydride; triethylamine; p-toluenesulfonyl chloride; zinc;
nickel;
In
tetrahydrofuran; methanol; hexane; dichloromethane; water; benzene;
DOI:10.1039/c39940002781
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 100 percent / p-ClC6H4NCO, NEt3 / benzene
2: H2, B(OMe)3 / Raney-Ni / methanol; H2O
3: D-camphor-10-sulfonic acid / CH2Cl2
4: Zn, TiCl4 / tetrahydrofuran; CH2Cl2
5: 43 percent / benzene / 48 h / 160 °C
6: 5percent Na-Hg / methanol
7: nBu4NF / tetrahydrofuran
8: 1) p-TsCl / 1) pyridine, 2) DMSO
9: 70 percent / iBu2AlH / hexane; CH2Cl2
With
sodium amalgam; Trimethyl borate; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; hydrogen; p-chlorphenylisocyanate; titanium tetrachloride; diisobutylaluminium hydride; triethylamine; p-toluenesulfonyl chloride; zinc;
nickel;
In
tetrahydrofuran; methanol; hexane; dichloromethane; water; benzene;
DOI:10.1039/c39940002781