N-(2-hydroxy-3-methyl-5-nitrophenyl)acetamide

Base Information

• Chemical Name: N-(2-hydroxy-3-methyl-5-nitrophenyl)acetamide
• CAS No.: 33150-08-2
• Molecular Formula: C₉H₁₀N₂O₄
• Molecular Weight: 210.189
• DSSTox Substance ID: DTXSID80404744
• NSC Number: 175409
• Wikidata: Q82209063
• Mol file: 33150-08-2.mol

Synonyms:33150-08-2;N-(2-hydroxy-3-methyl-5-nitrophenyl)acetamide;NSC175409;2'-Hydroxy-3'-methyl-5'-nitroacetanilide;6-Acetamido-4-nitro-o-kresol;DTXSID80404744;AKOS030211265;2-Hydroxy-3-methyl-5-nitroacetanilide;NSC 175409;NSC-175409

Chemical Property of N-(2-hydroxy-3-methyl-5-nitrophenyl)acetamide

Chemical Property:

• Vapor Pressure: 1.11E-07mmHg at 25°C
• Boiling Point: 420.9°C at 760 mmHg
• Flash Point: 208.4°C
• Density: 1.41g/cm³
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 210.06405680
• Heavy Atom Count: 15
• Complexity: 263

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1O)NC(=O)C)[N+](=O)[O-]

Technology Process of N-(2-hydroxy-3-methyl-5-nitrophenyl)acetamide

There total 2 articles about N-(2-hydroxy-3-methyl-5-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-6-methyl-4-nitro-phenol (6265-03-8) + acetic anhydride (108-24-7) → 6-Acetamido-4-nitro-o-kresol (33150-08-2)

Guidance literature:

With sodium hydroxide;

Reference yield:

→ 6-Acetamido-4-nitro-o-kresol (33150-08-2)

Guidance literature:

aus 4,6-Dinitro-o-kresol im Kaninchen;

Reference yield:

6-Acetamido-4-nitro-o-kresol (33150-08-2) → sulfuric acid mono-(2-acetylamino-6-methyl-4-nitro-phenyl ester)

Guidance literature:

With chlorosulfonic acid;

upstream raw materials:

2-amino-6-methyl-4-nitro-phenol

acetic anhydride