Chemical Property of 2-Hydroxyoleic acid
Chemical Property:
- Melting Point:47-50oC
- PSA：57.53000
- LogP:5.07930
- Storage Temp.:room temp
- Solubility.:DMSO: >20mg/mL
- XLogP3:6.5
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:15
- Exact Mass:298.25079494
- Heavy Atom Count:21
- Complexity:261
- Purity/Quality:
-
98%,99%, *data from raw suppliers
2-Hydroxy Oleic Acid *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xi
- Statements:
41
- Safety Statements:
26-39
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CCCCCCCCC=CCCCCCCC(C(=O)O)O
- Isomeric SMILES:CCCCCCCC/C=C\CCCCCCC(C(=O)O)O
- Recent EU Clinical Trials:A randomized, double-blind, placebo-controlled adjuvant trial in newly diagnosed primary glioblastoma subjects to assess the efficacy and safety of 2-hydroxyoleic acid (2-OHOA) in combination with radiotherapy and temozolomide standard of care treatment
-
Uses
An oleic acid synthetic analog that is an effective non-toxic anticancer drug with a wide spectrum against different types of cancer. An antihypertensive. 2OHOA has been used as:a modulator of the sphingolipid and glycerophospholipid pathway to study its effects on myelination in mice Charcot–Marie–Tooth type 1A (CMT1A) myelinopathy and myelinating dorsal root ganglia culturesin biophysical studies to study its effects on artificial membranesto study its interactions with major membrane lipid films
