Pentanedioic acid, 2-phenyl-, dimethyl ester, (R)-

Base Information

Chemical Name:Pentanedioic acid, 2-phenyl-, dimethyl ester, (R)-
CAS No.:56523-52-5
Molecular Formula:C₁₃H₁₆O₄
Molecular Weight:236.268
Hs Code.:
DSSTox Substance ID:DTXSID50462331
Nikkaji Number:J1.520.288B
Wikidata:Q82286848

Synonyms:Pentanedioic acid, 2-phenyl-, dimethyl ester, (R)-;56523-52-5;DTXSID50462331

Suppliers and Price of Pentanedioic acid, 2-phenyl-, dimethyl ester, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Pentanedioic acid, 2-phenyl-, dimethyl ester, (R)-

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:236.10485899
Heavy Atom Count:17
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CCC(C1=CC=CC=C1)C(=O)OC
Isomeric SMILES:COC(=O)CC[C@H](C1=CC=CC=C1)C(=O)OC

Technology Process of Pentanedioic acid, 2-phenyl-, dimethyl ester, (R)-

There total 4 articles about Pentanedioic acid, 2-phenyl-, dimethyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 101-41-7
benzeneacetic acid methyl ester

: 56523-53-6
dimethyl (S)-2-phenylglutarate

: 56523-52-5
dimethyl (R)-2-phenylglutarate

Guidance literature:: Product distribution; multistep reaction; also tert-butyl phenylacetate; other chiral crown ethers derived from camphor; application to asymmetric Michael addition;
DOI:10.1016/S0957-4166(00)86246-1

Reference yield:

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 101-41-7
benzeneacetic acid methyl ester

: 56523-53-6
2-Phenylglutarsaeure-dimethylester

: 56523-52-5
2-Phenylglutarsaeure-dimethylester

Guidance literature:: With potassium tert-butylate; crown ether 4a (R = benzyl); Product distribution; other crown ethers, other base: NaO^tBu; effect of cation and side chains at the crown; enantioselectivity;

Reference yield:

: 10436-86-9
dimethyl 2-phenylpentanedioate

: 56523-53-6
dimethyl (S)-2-phenylglutarate

: 56523-52-5
dimethyl (R)-2-phenylglutarate

Guidance literature:: With chiral crown ether; potassium tert-butylate; In toluene; at -78 ℃; for 0.133333h; Product distribution; deracemization; var. of crown ethers, solvent, temp., time;
DOI:10.1016/0040-4039(95)01150-G