(1R,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-2-one

Base Information

Chemical Name:(1R,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-2-one
CAS No.:56620-28-1
Molecular Formula:C8H13NO
Molecular Weight:139.197
Hs Code.:
DSSTox Substance ID:DTXSID20447115
Nikkaji Number:J887.288K

Synonyms:56620-28-1;(+/-)-tropan-2-one;(-)-Tropinone;(1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-2-ONE;(+)-2-Tropinone;SCHEMBL10610010;DTXSID20447115;VIZAOHGVLPCBMA-NKWVEPMBSA-N;MFCD12963607;AKOS037644349;AS-51648

Suppliers and Price of (1R,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
(1R,5S)-8-methyl-8-Azabicyclo[3.2.1]octan-2-one 97.00%
25G
$ 16100.00

AccelPharmtech
(1R,5S)-8-methyl-8-Azabicyclo[3.2.1]octan-2-one 97.00%
5G
$ 8450.00

AccelPharmtech
(1R,5S)-8-methyl-8-Azabicyclo[3.2.1]octan-2-one 97.00%
1G
$ 6090.00

Total 4 raw suppliers

Chemical Property of (1R,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-2-one

Chemical Property:

PSA：20.31000
LogP:0.75000
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:139.099714038
Heavy Atom Count:10
Complexity:167

Purity/Quality:

97% ^*data from raw suppliers

(1R,5S)-8-methyl-8-Azabicyclo[3.2.1]octan-2-one 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2CCC1C(=O)CC2
Isomeric SMILES:CN1[C@H]2CC[C@@H]1C(=O)CC2

Technology Process of (1R,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-2-one

There total 8 articles about (1R,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 484-93-5
ecgonidine

: 56620-28-1
(5S)-8-methyl-8-azabicyclo[3.2.1]octan-2-one

Guidance literature:: ecgonidine; With dmap; diphenyl phosphoryl azide; sodium carbonate; In dichloromethane; at 20 ℃; for 65h; Inert atmosphere;

With hydrogenchloride; In water; at 120 ℃; for 0.833333h; Inert atmosphere;

Reference yield:

: 53-21-4
(-)-cocaine hydrochloride

: 56620-28-1
(5S)-8-methyl-8-azabicyclo[3.2.1]octan-2-one

Guidance literature:: With hydrogenchloride; dmap; diphenyl phosphoryl azide; Yield given. Multistep reaction; 1.) reflux;
DOI:10.1016/S0040-4039(97)01276-8

Reference yield:

: 56620-28-1
(5S)-8-methyl-8-azabicyclo[3.2.1]octan-2-one

Guidance literature:: With methanol; sodium hypochlorite; water; folgenden Erhitzen des Reaktionsgemisches mit wss. Salzsaeure;
DOI:10.1021/ja01555a062