4-(Dichloromethyl)pyridine-2-carboxamide

Base Information

Chemical Name:4-(Dichloromethyl)pyridine-2-carboxamide
CAS No.:85148-96-5
Molecular Formula:C₇H₆Cl₂N₂O
Molecular Weight:205.043
Hs Code.:
NSC Number:370863
DSSTox Substance ID:DTXSID30321139
Wikidata:Q82078885

Synonyms:85148-96-5;NSC 370863;4-(dichloromethyl)pyridine-2-carboxamide;NSC370863;DTXSID30321139;AKOS004903743;NSC-370863

Suppliers and Price of 4-(Dichloromethyl)pyridine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4-(Dichloromethyl)pyridine-2-carboxamide

Chemical Property:

Vapor Pressure:7.45E-06mmHg at 25°C
Boiling Point:376.1°Cat760mmHg
Flash Point:181.2°C
Density:1.452g/cm³
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:203.9857182
Heavy Atom Count:12
Complexity:175

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=C(C=C1C(Cl)Cl)C(=O)N

Technology Process of 4-(Dichloromethyl)pyridine-2-carboxamide

There total 2 articles about 4-(Dichloromethyl)pyridine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

: 85148-98-7
4-Dichloromethyl-2-cyanopyridine

: 85148-96-5
2-Aminocarbonyl-4-dichloromethylpyridine

Guidance literature:: With silver nitrate; In ethanol; water; for 7h; Heating;
DOI:10.1055/s-1982-30085

Reference yield:

: 1620-76-4
2-Cyano-4-methylpyridin

: 85148-96-5
2-Aminocarbonyl-4-dichloromethylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / SO₂Cl₂, dibenzoyl peroxide / CCl₄ / 24 h / Heating; Irradiation

2: 27 percent / AgNO₃ / ethanol; H₂O / 7 h / Heating

With sulfuryl dichloride; silver nitrate; dibenzoyl peroxide; In tetrachloromethane; ethanol; water;
DOI:10.1055/s-1982-30085