2-Methyl-4-penten-1-ol

Base Information

• Chemical Name: 2-Methyl-4-penten-1-ol
• CAS No.: 5673-98-3
• Molecular Formula: C6H12O
• Molecular Weight: 100.161
• Mol file: 5673-98-3.mol

Synonyms:2S-methyl-4-penten-1-ol;2-methyl-4-pentenol;CTHUAOGQNZSMMC-UHFFFAOYSA;2-Methyl-4-penten-1-ol;4-Penten-1-ol,2-methyl;2-methyl-pent-4-en-1-ol;

Chemical Property of 2-Methyl-4-penten-1-ol

Chemical Property:

• Melting Point: 22.55°C (estimate)
• Refractive Index: 1.4289 (estimate)
• Boiling Point: 152.63°C (estimate)
• PKA: 14.99±0.10(Predicted)
• PSA: 20.23000
• Density: 0.8489 (estimate)
• LogP: 1.19090

Purity/Quality:

95% ^*data from raw suppliers

2-Methyl-4-penten-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methyl-4-penten-1-ol

There total 9 articles about 2-Methyl-4-penten-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

(4R,5S)-4-methyl-3-((S)-2-methylpent-4-enoyl)-5-phenyloxazolidin-2-one (80697-95-6) → 4-methyl-5-phenyloxazolidin-2-one (77943-39-6) + (S)-(-)-2-methyl-4-penten-1-ol (5673-98-3,63501-27-9,88080-30-2,63501-26-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; -70 deg C, 40 min; -78 deg C, 1 h; -78 to -20 deg C, 2 h;

DOI:10.1021/ja00216a026

Reference yield: 58.0%

(4R)-4-Benzyl-3-[(2S)-2-methyl-4-pentenoyl]-1,3-oxazolidin-2-one (175272-36-3) → (S)-(-)-2-methyl-4-penten-1-ol (5673-98-3,63501-27-9,88080-30-2,63501-26-8) + (R)-4-(phenylmethyl)-2-oxazolidinone (40217-17-2,90719-32-7,120574-96-1,102029-44-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 1h;

DOI:10.1002/(SICI)1521-3765(19990903)5:9<2492::AID-CHEM2492>3.0.CO;2-R

Reference yield: 52.0%

allyltitanium triphenoxide (130004-39-6) + methyloxirane (75-56-9,16033-71-9) → hex-5-en-2-ol (17397-24-9,17397-29-4,54774-27-5,626-94-8) + 2-methylpent-4-en-1-ol (5673-98-3)

Guidance literature:

In tetrahydrofuran; Yields of byproduct given; from -78 deg C to RT;

DOI:10.1039/c39900000906

upstream raw materials:

(4R,5S)-4-methyl-3-((S)-2-methylpent-4-enoyl)-5-phenyloxazolidin-2-one

(R)-2-Methyl-pent-4-enoic acid (1S,2R,4R)-1-[(dicyclohexylsulfamoyl)-methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester

(4R)-4-Benzyl-3-[(2S)-2-methyl-4-pentenoyl]-1,3-oxazolidin-2-one

(1''S,2S,2'R)-1-[2'-(1''-tert-butyldiphenylsiloxyethyl)-4'H-benzo[d][1',3']oxazin-1'-yl]-2-methylpent-4-en-1-one

Downstream raw materials:

(3S)-4-Benzyloxy-3-methyl-butyraldehyde

(3S, 3'S,3aS, 5R , 6R,6aS)-(E)-2-(4'-benzyloxy-3'-methylbutylidene)-3,6-dimethyl-5-vinyl-hexahydro-pentalen-1-one

(4R,5S)-3-[(2R,3S,4S)-3-hydroxy-2,4-dimethylhept-6-enoyl]-4-methyl-5-phenyl-1,3-oxazolidin-2-one

(4R,5S)-3-[(2R,3S,4S)-3-(methoxymethoxy)-2,4-dimethylhept-6-enoyl]-4-methyl-5-phenyl-1,3-oxazolidin-2-one