Benzoic acid, 4-(hexyloxy)-, 4-formylphenyl ester

Base Information

• Chemical Name: Benzoic acid, 4-(hexyloxy)-, 4-formylphenyl ester
• CAS No.: 56800-31-8
• Molecular Formula: C20H22O4
• Molecular Weight: 326.392
• Mol file: 56800-31-8.mol

Synonyms:

Chemical Property of Benzoic acid, 4-(hexyloxy)-, 4-formylphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4-(hexyloxy)-, 4-formylphenyl ester

There total 10 articles about Benzoic acid, 4-(hexyloxy)-, 4-formylphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.7%

para-hexyloxybenzoic acid (1142-39-8) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 4-formylphenyl 4-hexyloxybenzoate (56800-31-8)

Guidance literature:

para-hexyloxybenzoic acid; 4-hydroxy-benzaldehyde; With dmap; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

With dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bioorg.2020.104170

Reference yield:

4-hexyloxybenzoyl chloride (39649-71-3) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 4-formylphenyl 4-hexyloxybenzoate (56800-31-8)

Guidance literature:

In pyridine; benzene; Yield given; 12 h, 25 deg C; 1 h, 80 deg C;

Reference yield:

1-bromo-hexane (111-25-1) → 4-formylphenyl 4-hexyloxybenzoate (56800-31-8)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / methanol / Heating

2: dimethyl aminopyridine; dicyclohexylcarbodiimide / CH₂Cl₂ / 20 °C

With potassium hydroxide; dicyclohexyl-carbodiimide; In methanol; dichloromethane;

DOI:10.1080/15421400601150379

upstream raw materials:

para-hexyloxybenzoic acid

4-hydroxy-benzaldehyde

4-hexyloxybenzoyl chloride

1-bromo-hexane

Downstream raw materials:

4-Hexyloxy-benzoic acid 4-[4-oxo-3-pentyl-2-thioxo-thiazolidin-(5Z)-ylidenemethyl]-phenyl ester

4-Hexyloxy-benzoic acid 4-[3-heptyl-4-oxo-2-thioxo-thiazolidin-(5Z)-ylidenemethyl]-phenyl ester

4-Hexyloxy-benzoic acid 4-{[(E)-4-ethyl-phenylimino]-methyl}-phenyl ester

4-Hexyloxy-benzoic acid 4-[3-butyl-4-oxo-2-thioxo-thiazolidin-(5Z)-ylidenemethyl]-phenyl ester

Refernces

• 1、 Huang, Chiung-Cheng,Huang, Yu-Chang,Hsieh, Wei-Cheng,Chen, Yen-Jung,Jiang, Shi-Kai,Chen, Bo-Hao,Hsu, I.-Jui,Lee, Jey-Jau. "The effects of molecular structure and functional group of a rodlike Schiff base mesogen on blue phase stabilization in a chiral system". supporting information. p. 1743 - 1756. Retrieved 2019/01/28.
• 2、 Huang, Chiung-Cheng,Wu, Zong-Ye,Sie, Bing-Han,Chou, We-Hao,Huang, Yu-Chang,Yu, Mei-Ching,Chen, Bo-Hao,Hsu, I-Jui,Wu, Lai-Chin,Lee, Jey-Jau. "Effect of the Functional Groups of Racemic Rodlike Schiff Base Mesogens on the Stabilization of Blue Phase in Binary Mixture Systems". . p. 12736 - 12754. Retrieved 2018/05/14.