2-Phenylpyrazolo[1,5-a]pyridine

Base Information

• Chemical Name: 2-Phenylpyrazolo[1,5-a]pyridine
• CAS No.: 56983-95-0
• Molecular Formula: C13H10N2
• Molecular Weight: 194.236
• DSSTox Substance ID: DTXSID90575873
• Nikkaji Number: J1.126.046B
• Wikidata: Q82465310
• Mol file: 56983-95-0.mol

Synonyms:2-Phenylpyrazolo[1,5-a]pyridine;56983-95-0;Pyrazolo[1,5-a]pyridine, 2-phenyl-;SCHEMBL5953401;DTXSID90575873;HFOAXDYGZAQNTI-UHFFFAOYSA-N;2-phenyl-pyrazolo[1,5-a]pyridine;AKOS006374037;G66036

Chemical Property of 2-Phenylpyrazolo[1,5-a]pyridine

Chemical Property:

• PSA: 17.30000
• LogP: 3.00130
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 194.084398327
• Heavy Atom Count: 15
• Complexity: 211

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NN3C=CC=CC3=C2

Technology Process of 2-Phenylpyrazolo[1,5-a]pyridine

There total 42 articles about 2-Phenylpyrazolo[1,5-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2,4,6-Trimethyl-benzenesulfonate1-amino-2-phenylethynyl-pyridinium; (76943-42-5) → 2-phenylpyrazolo[1,5-a]pyridine (56983-95-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 6h; Ambient temperature;

Reference yield: 98.0%

(Z)-5-(but-1-en-3-yn-1-yl)-3-phenyl-1H-pyrazole (1394234-79-7) → 2-phenylpyrazolo[1,5-a]pyridine (56983-95-0)

Guidance literature:

With silver hexafluoroantimonate; (triphenylphosphine)gold(I) chloride; In tetrahydrofuran; at 20 ℃; for 5h;

DOI:10.1039/c2ob25973g

Reference yield: 95.0%

ethyl 2-phenylpyrazolo<1,5-a>pyridine-3-carboxylate (51065-76-0) → 2-phenylpyrazolo[1,5-a]pyridine (56983-95-0)

Guidance literature:

With hydrogen bromide; In water;

upstream raw materials:

1-phenyl-2-(2-pyridinyl)ethylamine

3-(α-hydroxybenzyl)-2-phenylpyrazolo<1,5-a>pyridine

2,4,6-Trimethyl-benzenesulfonate1-amino-2-phenylethynyl-pyridinium;

2-Phenyl-pyrazolo[1,5-a]pyridine-4-carboxylic acid ethyl ester

Downstream raw materials:

bis(2-phenylpyrazolo<1,5-a>pyrid-3-yl)methane

phenylbis(2-phenylpyrazolo<1,5-a>pyrid-3-yl)methane

2-phenyl-pyrazolo[1,5-a]pyridine-3-carbaldehyde