6-methyl-4H-furo[3,2-c]pyran-4-one

Base Information

• Chemical Name: 6-methyl-4H-furo[3,2-c]pyran-4-one
• CAS No.: 57053-19-7
• Molecular Formula: C₈H₆O₃
• Molecular Weight: 150.134
• DSSTox Substance ID: DTXSID20363169
• Wikidata: Q82146755
• Mol file: 57053-19-7.mol

Synonyms:6-methyl-4H-furo[3,2-c]pyran-4-one;57053-19-7;6-methylfuro[3,2-c]pyran-4-one;DTXSID20363169;MFCD01443821;AKOS006277895;10M-720

Chemical Property of 6-methyl-4H-furo[3,2-c]pyran-4-one

Chemical Property:

• Melting Point: 118-120 °C(Solv: cyclohexane (110-82-7))
• Boiling Point: 245.2±40.0 °C(Predicted)
• PSA: 43.35000
• Density: 1.273±0.06 g/cm3(Predicted)
• LogP: 1.69440
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 150.031694049
• Heavy Atom Count: 11
• Complexity: 219

Purity/Quality:

6-methyl-4H-Furo[3,2-c]pyran-4-one 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(C=CO2)C(=O)O1

Technology Process of 6-methyl-4H-furo[3,2-c]pyran-4-one

There total 3 articles about 6-methyl-4H-furo[3,2-c]pyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

Carboxy-3 one-4 methyl-6 4-H furo<3,2-c>pyranne (69444-02-6) → One-4 methyl-6 4-H furo<3,2-c>pyranne (57053-19-7)

Guidance literature:

copper; In quinoline; for 2h; Heating;

DOI:10.1002/jhet.5570220519

Reference yield:

Acetonyl-2 dicarboxy-3,4 furanne (69459-92-3) → One-4 methyl-6 4-H furo<3,2-c>pyranne (57053-19-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / Ac₂O / 1 h / Heating

2: 92 percent / powder Cu / quinoline / 2 h / Heating

With acetic anhydride; copper; In quinoline;

DOI:10.1002/jhet.5570220519

Reference yield:

Acetonyl-2 dicarbomethoxy-3,4 furanne (69443-91-0) → One-4 methyl-6 4-H furo<3,2-c>pyranne (57053-19-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 87 percent / KOH / ethanol; H₂O / 1 h / Heating

2: 77 percent / Ac₂O / 1 h / Heating

3: 92 percent / powder Cu / quinoline / 2 h / Heating

With potassium hydroxide; acetic anhydride; copper; In quinoline; ethanol; water;

DOI:10.1002/jhet.5570220519

upstream raw materials:

Carboxy-3 one-4 methyl-6 4-H furo<3,2-c>pyranne

Acetonyl-2 dicarboxy-3,4 furanne

Acetonyl-2 dicarbomethoxy-3,4 furanne

Downstream raw materials:

4-[2-(3,4-dihydroxy-phenyl)-2-oxo-ethylsulfanyl]-5,6-dimethyl-furo[3,2-c]pyridinium; chloride

5,6-dimethyl-4-(2-oxo-2-phenyl-ethylsulfanyl)-furo[3,2-c]pyridinium; bromide

5-(4-hydroxy-phenyl)-6-methyl-5H-furo[3,2-c]pyridin-4-one

2-(2-Oxopropyl)-3-furancarbaldehyd