1-(3-Chloro-1-phenylpropoxy)-2-methoxybenzene

Base Information

Chemical Name:1-(3-Chloro-1-phenylpropoxy)-2-methoxybenzene
CAS No.:57226-60-5
Molecular Formula:C16H17ClO2
Molecular Weight:276.763
Hs Code.:
DSSTox Substance ID:DTXSID30510344

Synonyms:1-(3-Chloro-1-phenylpropoxy)-2-methoxybenzene;57226-60-5;SCHEMBL6725319;DTXSID30510344

Suppliers and Price of 1-(3-Chloro-1-phenylpropoxy)-2-methoxybenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(3-Chloro-1-phenylpropoxy)-2-methoxybenzene

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:276.0917075
Heavy Atom Count:19
Complexity:241

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC=C1OC(CCCl)C2=CC=CC=C2

Technology Process of 1-(3-Chloro-1-phenylpropoxy)-2-methoxybenzene

There total 4 articles about 1-(3-Chloro-1-phenylpropoxy)-2-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21763-00-8
1-bromo-3-chloro-1-phenylpropane

: 90-05-1
2-methoxy-phenol

: 57226-60-5
3-chloro-1-(o-methoxyphenoxy)propylbenzene

Guidance literature:: 2-methoxy-phenol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 0.5h; Inert atmosphere; Sonication; Cooling with ice;

1-bromo-3-chloro-1-phenylpropane; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 12h; chemoselective reaction; Inert atmosphere; Cooling with ice;
DOI:10.1124/mol.113.091249

Reference yield:

: 21763-00-8
1-bromo-3-chloro-1-phenylpropane

: 57226-60-5
3-chloro-1-(o-methoxyphenoxy)propylbenzene

Guidance literature:

Reference yield:

: 104-52-9
phenylpropyl chloride

: 57226-60-5
3-chloro-1-(o-methoxyphenoxy)propylbenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-Bromosuccinimide; dibenzoyl peroxide / chlorobenzene / 4 h / 85 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 20 °C / Inert atmosphere; Sonication; Cooling with ice

2.2: 12 h / 20 °C / Inert atmosphere; Cooling with ice

With N-Bromosuccinimide; sodium hydride; dibenzoyl peroxide; In N,N-dimethyl-formamide; chlorobenzene; mineral oil;
DOI:10.1124/mol.113.091249