methyl 5-amino-1H-benzimidazole-2-carbamate

Base Information

Chemical Name:methyl 5-amino-1H-benzimidazole-2-carbamate
CAS No.:57438-18-3
Molecular Formula:C₉H₁₀N₄O₂
Molecular Weight:206.204
Hs Code.:
DSSTox Substance ID:DTXSID20598691
Wikidata:Q82494480

Synonyms:57438-18-3;methyl 5-amino-1H-benzimidazole-2-carbamate;methyl N-(6-amino-1H-benzimidazol-2-yl)carbamate;SCHEMBL5351438;DTXSID20598691;Methyl (6-amino-1H-benzimidazol-2-yl)carbamate

Suppliers and Price of methyl 5-amino-1H-benzimidazole-2-carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
N-(6-amino-1H-benzimidazol-2-yl)-Carbamicacidmethylester 97.00%
25G
$ 4320.00

AccelPharmtech
N-(6-amino-1H-benzimidazol-2-yl)-Carbamicacidmethylester 97.00%
5G
$ 2330.00

AccelPharmtech
N-(6-amino-1H-benzimidazol-2-yl)-Carbamicacidmethylester 97.00%
1G
$ 2070.00

Total 0 raw suppliers

Chemical Property of methyl 5-amino-1H-benzimidazole-2-carbamate

Chemical Property:

PSA：96.52000
LogP:1.91820
XLogP3:0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:206.08037557
Heavy Atom Count:15
Complexity:248

Purity/Quality:: N-(6-amino-1H-benzimidazol-2-yl)-Carbamicacidmethylester 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)NC1=NC2=C(N1)C=C(C=C2)N

Technology Process of methyl 5-amino-1H-benzimidazole-2-carbamate

There total 4 articles about methyl 5-amino-1H-benzimidazole-2-carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 40483-97-4
methyl 5-nitrobenzoimidazole-2-carbamate

: 57438-18-3
methyl 5-amino-1H-benzimidazole-2-carbamate

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 80 ℃; for 20h; under 2585.7 Torr;
DOI:10.1021/jm00081a016

Reference yield:

: C₁₃H₁₅N₃O₄S

: 57438-18-3
C₉H₁₀N₄O₂

Guidance literature:: With sulfuric acid; nitric acid; at 20 ℃; for 2.5h;

Reference yield:

: 99-56-9
4-Nitrophenylene-1,2-diamine

: 57438-18-3
methyl 5-amino-1H-benzimidazole-2-carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) aq. NaOH / 1.) 10-15 deg C, 2.) 95 deg C, 2 h

2: 68 percent / H₂ / 5percent Pd/C / methanol / 20 h / 80 °C / 2585.7 Torr

With sodium hydroxide; hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00081a016