7-Hydroxy-3-(2-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one

Base Information

Chemical Name:7-Hydroxy-3-(2-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one
CAS No.:57462-46-1
Molecular Formula:C₁₆H₁₄O₅
Molecular Weight:286.284
Hs Code.:
DSSTox Substance ID:DTXSID40984698
Nikkaji Number:J19.190F
Wikidata:Q105310340
Metabolomics Workbench ID:121852
ChEMBL ID:CHEMBL1087009

Synonyms:2,3-dihydro-7-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one;vestitone

Suppliers and Price of 7-Hydroxy-3-(2-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
rac-Vestitone
10mg
$ 185.00

Medical Isotopes, Inc.
rac-Vestitone
1 g
$ 2200.00

Medical Isotopes, Inc.
rac-Vestitone
100 mg
$ 650.00

Total 0 raw suppliers

Chemical Property of 7-Hydroxy-3-(2-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one

Chemical Property:

Melting Point:>172°C (dec.)
PSA：75.99000
LogP:2.46530
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:286.08412354
Heavy Atom Count:21
Complexity:385

Purity/Quality:: rac-Vestitone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)C2COC3=C(C2=O)C=CC(=C3)O)O
Uses Vestitone reductase catalyzes a stereospecific NADPH-dependent reduction of (3R)-vestitone in the bio sysnthesis of antimicrobial isoflavonoid phytoalexin medicarpin.

Technology Process of 7-Hydroxy-3-(2-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one

There total 3 articles about 7-Hydroxy-3-(2-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 129780-43-4
7-ethoxymethoxy-2',4'-dimethoxyisoflavanone

: 57462-46-1,66211-83-4
2',7-dihydroxy-4'-methoxyisoflavanone

Guidance literature:: With aluminium trichloride; In acetonitrile; for 8h; Heating;

Reference yield:

: 1855-30-7
1-(2,4-dihydroxyphenyl)-2-(2,4-dimethoxyphenyl)ethanone

: 57462-46-1,66211-83-4
2',7-dihydroxy-4'-methoxyisoflavanone

Guidance literature:: Multi-step reaction with 3 steps

1: K₂CO₃ / acetone

2: 0.65 g / diethylamine / methanol / 2 h / Heating

3: 0.30 g / AlCl₃ / acetonitrile / 8 h / Heating

With aluminium trichloride; potassium carbonate; diethylamine; In methanol; acetone; acetonitrile;

Reference yield:

: 129780-42-3
4'-ethoxymethoxy-2'-hydroxyphenyl-2,4-dimethoxybenzyl ketone

: 57462-46-1,66211-83-4
2',7-dihydroxy-4'-methoxyisoflavanone

Guidance literature:: Multi-step reaction with 2 steps

1: 0.65 g / diethylamine / methanol / 2 h / Heating

2: 0.30 g / AlCl₃ / acetonitrile / 8 h / Heating

With aluminium trichloride; diethylamine; In methanol; acetonitrile;