Methyl 3-(piperidin-1-yl)benzoate

Base Information

Chemical Name:Methyl 3-(piperidin-1-yl)benzoate
CAS No.:57489-59-5
Molecular Formula:C13H17NO2
Molecular Weight:219.283
Hs Code.:
DSSTox Substance ID:DTXSID20428085

Synonyms:57489-59-5;Methyl 3-(piperidin-1-yl)benzoate;3-Piperidin-1-yl-benzoic acid methyl ester;Benzoic acid, 3-(1-piperidinyl)-, methyl ester;methyl 3-piperidin-1-ylbenzoate;Methyl 3-(1-piperidinyl)benzoate;SCHEMBL4203044;DTXSID20428085;BOFFXEJPALDANU-UHFFFAOYSA-N;Methyl3-(piperidin-1-yl)benzoate;AS-0590;MB04101

Suppliers and Price of Methyl 3-(piperidin-1-yl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Methyl 3-(piperidin-1-yl)benzoate

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:219.125928785
Heavy Atom Count:16
Complexity:236

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC(=CC=C1)N2CCCCC2

Technology Process of Methyl 3-(piperidin-1-yl)benzoate

There total 12 articles about Methyl 3-(piperidin-1-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 168162-28-5
methyl 3-(2-oxopiperidin-1-yl)benzoate

: 57489-59-5
3-piperidin-1-yl-benzoic acid methyl ester

Guidance literature:: With borane-THF; In tetrahydrofuran; for 1h; Heating;
DOI:10.1021/jm960669+

Reference yield: 86.0%

: 110-89-4
piperidine

: 618-91-7
methyl 3-iodo-benzoate

: 57489-59-5
3-piperidin-1-yl-benzoic acid methyl ester

Guidance literature:: With copper(l) iodide; potassium carbonate; L-proline; In dimethyl sulfoxide; at 60 ℃; for 8h;
DOI:10.1016/j.bmc.2016.03.014

Reference yield: 70.0%

: 110-89-4
piperidine

: 2905-65-9
methyl 3-chlorobenzoate

: 57489-59-5
3-piperidin-1-yl-benzoic acid methyl ester

Guidance literature:: With caesium carbonate; P(i-BuNCH₂)3CMe; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In toluene; at 110 ℃; for 24h;
DOI:10.1021/jo034994y