15,16-Dihydro-16-hydroxy-11-methylcyclopenta(a)phenanthren-17-one

Base Information

• Chemical Name: 15,16-Dihydro-16-hydroxy-11-methylcyclopenta(a)phenanthren-17-one
• CAS No.: 24684-56-8
• Molecular Formula: C₁₈H₁₄O₂
• Molecular Weight: 262.308
• UNII: HZR9Y942IB
• DSSTox Substance ID: DTXSID00947628
• Nikkaji Number: J34.884H
• Wikidata: Q27280176
• Mol file: 24684-56-8.mol

Synonyms:24684-56-8;15,16-Dihydro-16-hydroxy-11-methylcyclopenta(a)phenanthren-17-one;HZR9Y942IB;15,16-Dihydro-16-hydroxy-11-methyl-17H-cyclopenta(a)phenanthren-17-one;17H-Cyclopenta(a)phenanthren-17-one, 15,16-dihydro-16-hydroxy-11-methyl-;BRN 2590834;UNII-HZR9Y942IB;DTXSID00947628;Q27280176;GONA-1,3,5,7,9,11,13-HEPTAEN-17-ONE, 16-HYDROXY-11-METHYL-;16-Hydroxy-11-methylgona-1(10),2,4,6,8(14),9(11),12-heptaen-17-one

Chemical Property of 15,16-Dihydro-16-hydroxy-11-methylcyclopenta(a)phenanthren-17-one

Chemical Property:

• Vapor Pressure: 7.37E-12mmHg at 25°C
• Refractive Index: 1.5200 (estimate)
• Boiling Point: 525.2°Cat760mmHg
• Flash Point: 221.8°C
• PSA: 37.30000
• Density: 1.334g/cm³
• LogP: 3.40110
• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 262.099379685
• Heavy Atom Count: 20
• Complexity: 404

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(CC(C2=O)O)C3=C1C4=CC=CC=C4C=C3

Technology Process of 15,16-Dihydro-16-hydroxy-11-methylcyclopenta(a)phenanthren-17-one

There total 1 articles about 15,16-Dihydro-16-hydroxy-11-methylcyclopenta(a)phenanthren-17-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 16-hydroxy-11-methyl-15,16-dihydrocyclopenta[a]phenanthren-17-one (24684-56-8)

Guidance literature:

DOI:10.1039/j39690002484

Reference yield:

16-hydroxy-11-methyl-15,16-dihydrocyclopenta[a]phenanthren-17-one (24684-56-8) → (16S,17S)-11-Methyl-16,17-dihydro-15H-cyclopenta[a]phenanthrene-16,17-diol (42123-09-1)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1039/P19730001255

Reference yield:

16-hydroxy-11-methyl-15,16-dihydrocyclopenta[a]phenanthren-17-one (24684-56-8) → 11-Methyl-15,17-dihydro-cyclopenta[a]phenanthren-16-one (42123-04-6)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄

2: aq. H₂SO₄ / tetrahydrofuran

With sodium tetrahydroborate; sulfuric acid; In tetrahydrofuran;

DOI:10.1039/P19730001255

Downstream raw materials:

(16S,17S)-11-Methyl-16,17-dihydro-15H-cyclopenta[a]phenanthrene-16,17-diol

11-Methyl-15,17-dihydro-cyclopenta[a]phenanthren-16-one