2-Hydroxycyclopentane-1-carbonitrile

Base Information

Chemical Name:2-Hydroxycyclopentane-1-carbonitrile
CAS No.:57836-12-1
Molecular Formula:C₆H₉NO
Molecular Weight:111.144
Hs Code.:
European Community (EC) Number:871-512-7
DSSTox Substance ID:DTXSID20499795

Synonyms:2-hydroxycyclopentane-1-carbonitrile;57836-12-1;2-Hydroxycyclopentanecarbonitrile;SCHEMBL6743146;DTXSID20499795;AKOS009434712;(1R,2S)-2-hydroxycyclopentanecarbonitrile;EN300-61208;Z409438998

Suppliers and Price of 2-Hydroxycyclopentane-1-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-hydroxycyclopentane-1-carbonitrile
100mg
$ 285.00

TRC
2-hydroxycyclopentane-1-carbonitrile
50mg
$ 175.00

American Custom Chemicals Corporation
2-HYDROXYCYCLOPENTANE-1-CARBONITRILE 95.00%
5G
$ 2181.31

American Custom Chemicals Corporation
2-HYDROXYCYCLOPENTANE-1-CARBONITRILE 95.00%
2.5G
$ 1635.30

American Custom Chemicals Corporation
2-HYDROXYCYCLOPENTANE-1-CARBONITRILE 95.00%
1G
$ 1070.84

AK Scientific
2-Hydroxycyclopentane-1-carbonitrile
10g
$ 3246.00

AK Scientific
2-Hydroxycyclopentane-1-carbonitrile
2.5g
$ 1535.00

Total 6 raw suppliers

Chemical Property of 2-Hydroxycyclopentane-1-carbonitrile

Chemical Property:

PSA：44.02000
LogP:0.67098
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:111.068413911
Heavy Atom Count:8
Complexity:124

Purity/Quality:

99% ^*data from raw suppliers

2-hydroxycyclopentane-1-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C(C1)O)C#N

Technology Process of 2-Hydroxycyclopentane-1-carbonitrile

There total 5 articles about 2-Hydroxycyclopentane-1-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 285-67-6
Cyclopentene oxide

: 143-33-9,25596-52-5
sodium cyanide

: 57836-12-1,63578-08-5,68455-39-0,70367-34-9,133725-25-4
trans-2-Hydroxycyclopentanecarbonitrile

Guidance literature:: With hydrogenchloride; In water; at -10 ℃; for 168h;

Reference yield:

: 131750-48-6
(1S,2R)-2-Trimethylsilanyloxy-cyclopentanecarbonitrile

: 57836-12-1,63578-08-5,68455-39-0,70367-34-9,133725-25-4
trans-2-Hydroxycyclopentanecarbonitrile

Guidance literature:: With potassium fluoride; In methanol;
DOI:10.1021/ja005794w

Reference yield:

: 142-29-0
cyclopentene

: 57836-12-1,63578-08-5,68455-39-0,70367-34-9,133725-25-4
trans-2-Hydroxycyclopentanecarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: [-OC(C₆H₅)2CH₂CH₂C(C₆H₅)2O-]Zr(O-tBu)2; Ph₃PO; bis(trimethylsilyl)peroxide / 1,2-dichloro-ethane / 5 h / 20 °C

2: KF / methanol

With potassium fluoride; [-OC(C₆H₅)2CH₂CH₂C(C₆H₅)2O-]Zr(O-tBu)2; bis-trimethylsilanyl peroxide; Triphenylphosphine oxide; In methanol; 1,2-dichloro-ethane;
DOI:10.1021/ja005794w