GW806742X

Base Information

Chemical Name:GW806742X
CAS No.:579515-63-2
Molecular Formula:C25H22F3N7O4S
Molecular Weight:573.54700
Hs Code.:
Mol file:579515-63-2.mol

Synonyms:Benzenesulfonamide, 3-[[4-[methyl[4-[[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]phenyl]amino]-2-pyrimidinyl]amino]-;3-[[4-[Methyl[4-[[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]phenyl]amino]-2-pyrimidinyl]amino]benzenesulfonamide;

Suppliers and Price of GW806742X

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
GW806742X >98%
250 mg
$ 1200.00

DC Chemicals
GW806742X >98%
1 g
$ 2500.00

DC Chemicals
GW806742X >98%
100 mg
$ 650.00

ChemScene
GW806742X 98.09%
5mg
$ 60.00

ChemScene
GW806742X 98.09%
100mg
$ 450.00

American Custom Chemicals Corporation
GW806742X 95.00%
5MG
$ 501.93

AK Scientific
GW806742X
10mg
$ 340.00

AK Scientific
GW806742X
100mg
$ 1470.00

Adipogen Life Sciences
GW806742X ≥95%
50 mg
$ 918.00

Total 17 raw suppliers

Chemical Property of GW806742X

Chemical Property:

PKA:10.09±0.60(Predicted)
PSA：159.95000
Density:1.524±0.06 g/cm3(Predicted)
LogP:7.17820

Purity/Quality:

99%, ^*data from raw suppliers

GW806742X >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of GW806742X

There total 5 articles about GW806742X which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

: 3-((4-((4-aminophenyl)(methyl)amino)pyrimidin-2-yl)amino)benzene sulfonamide

: 35037-73-1
1-isocyanato-4-trifluoromethoxy-benzene

: 579515-63-2
3-((4-(methyl-(4-(3-(4-(trifluoromethoxy)phenyl)ureido)phenyl)amino)pyrimidin-2-yl)amino)benzenesulfonamide

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 16h; Inert atmosphere;

Reference yield:

: 3-((4-(methyl(4-nitrophenyl)amino)pyrimidin-2-yl)amino)benzene sulfonamide

: 579515-63-2
3-((4-(methyl-(4-(3-(4-(trifluoromethoxy)phenyl)ureido)phenyl)amino)pyrimidin-2-yl)amino)benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: zinc; ammonium chloride / ethanol / 2 h / 90 °C

2: N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere

With ammonium chloride; zinc; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 579515-63-2
3-((4-(methyl-(4-(3-(4-(trifluoromethoxy)phenyl)ureido)phenyl)amino)pyrimidin-2-yl)amino)benzenesulfonamide

Guidance literature:: Multi-step reaction with 5 steps

1: potassium carbonate / dimethyl sulfoxide / 70 °C / Inert atmosphere

2: potassium carbonate / N,N-dimethyl-formamide / 80 °C

3: hydrogenchloride / 1,4-dioxane; water / 2 h / 160 °C / Microwave irradiation

4: zinc; ammonium chloride / ethanol / 2 h / 90 °C

5: N,N-dimethyl-formamide / 16 h / 20 °C / Inert atmosphere

With hydrogenchloride; potassium carbonate; ammonium chloride; zinc; In 1,4-dioxane; ethanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide;