(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)(2,4-dichlorophenyl)methanone

Base Information

Chemical Name:(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)(2,4-dichlorophenyl)methanone
CAS No.:58011-97-5
Molecular Formula:C12H9Cl3N2O
Molecular Weight:303.575
Hs Code.:
DSSTox Substance ID:DTXSID60515387
Wikidata:Q82376242

Synonyms:(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)(2,4-dichlorophenyl)methanone;58011-97-5;SCHEMBL10751427;DTXSID60515387;JXKPGKSFHPGZEQ-UHFFFAOYSA-N;5-chloro-4-(2,4-dichlorobenzoyl)-1,3-dimethylpyrazole

Suppliers and Price of (5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)(2,4-dichlorophenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)(2,4-dichlorophenyl)methanone

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:301.978046
Heavy Atom Count:18
Complexity:328

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN(C(=C1C(=O)C2=C(C=C(C=C2)Cl)Cl)Cl)C

Technology Process of (5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)(2,4-dichlorophenyl)methanone

There total 5 articles about (5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)(2,4-dichlorophenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.3%

: 58011-37-3
1,3-dimethyl-4-(2,4-dichlorobenzoyl)-5-mercaptopyrazole

: 58011-97-5
(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)(2,4-dichlorophenyl)methanone

Guidance literature:

Reference yield: 71.6%

: 58010-98-3
4-(2,4-dichlorobenzoyl)-1,3-dimethyl-5-hydroxypyrazole

: 58011-97-5
(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)(2,4-dichlorophenyl)methanone

Guidance literature:: With trichlorophosphate; for 6h; Reflux;
DOI:10.1080/10426507.2013.829832

Reference yield:

: 2749-59-9
1,3-dimethyl-5-pyrazolone

: 58011-97-5
(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)(2,4-dichlorophenyl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / Reflux

2: potassium carbonate / 1,4-dioxane / Reflux

3: trichlorophosphate / 6 h / Reflux

With potassium carbonate; triethylamine; trichlorophosphate; In 1,4-dioxane; dichloromethane; 2: |Fries Phenol Ester Rearrangement;
DOI:10.1080/10426507.2013.829832