Diethyl 4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Base Information

Chemical Name:Diethyl 4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS No.:58029-72-4
Molecular Formula:C19H22BrNO4
Molecular Weight:408.292
Hs Code.:
European Community (EC) Number:651-820-6
Nikkaji Number:J2.205.100H
ChEMBL ID:CHEMBL2063644
Mol file:58029-72-4.mol

Synonyms:diethyl 4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;58029-72-4;3,5-diethyl 4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;Oprea1_667103;Oprea1_842401;SCHEMBL3017205;CHEMBL2063644;UJDAVWDVWMBSLW-UHFFFAOYSA-N;STK369305;AKOS000296834;CS-0298835;EU-0056724;EN300-23219103;SR-01000403369;SR-01000403369-1;Z56871549;3,5-Pyridinedicarboxylic acid, 4-(4-bromophenyl)-1,4-dihydro-2,6-dimethyl-, diethyl ester;4-(4-BR-PH)-2,6-DIMETHYL-1,4-2H-PYRIDINE-3,5-DICARBOXYLIC ACID DIETHYL ESTER;diethyl 4-(4- bromophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate;Diethyl 4-(4-bromophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate;diethyl 4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylate

Suppliers and Price of Diethyl 4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Diethyl 4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property:

PSA：64.63000
LogP:4.13890
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:407.07322
Heavy Atom Count:25
Complexity:548

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(NC(=C(C1C2=CC=C(C=C2)Br)C(=O)OCC)C)C

Technology Process of Diethyl 4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

There total 4 articles about Diethyl 4-(4-bromophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 141-97-9
ethyl acetoacetate

: 1122-91-4
4-bromo-benzaldehyde

: 58029-72-4
4-(4-bromo-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester

Guidance literature:: With ammonium acetate; In ethanol; water; at 20 ℃; for 2h;
DOI:10.21608/EJCHEM.2021.88473.4256

Reference yield: 91.0%

: 1122-91-4
4-bromo-benzaldehyde

: 3-Oxo-butaneperoxoic acid ethyl ester

: 58029-72-4
4-(4-bromo-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester

Guidance literature:: With ammonium acetate; In neat (no solvent); at 60 ℃; for 0.333333h;
DOI:10.1039/c3ta12476b

Reference yield: 87.0%

: 631-61-8,92206-38-7
ammonium acetate

: 141-97-9
ethyl acetoacetate

: 1122-91-4
4-bromo-benzaldehyde

: 58029-72-4
4-(4-bromo-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester

Guidance literature:: With Silica-sulphonic acid-[BMIM][PF₆]; In neat (no solvent); at 60 ℃; for 0.25h; Green chemistry;
DOI:10.1039/c4gc00923a