2-(Acetyloxy)-4-ethoxybenzoic acid

Base Information

Chemical Name:2-(Acetyloxy)-4-ethoxybenzoic acid
CAS No.:58138-64-0
Molecular Formula:C₁₁H₁₂O₅
Molecular Weight:224.213
Hs Code.:
DSSTox Substance ID:DTXSID70494513
Wikidata:Q82341921

Synonyms:58138-64-0;DTXSID70494513;2-(Acetyloxy)-4-ethoxybenzoic acid

Suppliers and Price of 2-(Acetyloxy)-4-ethoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-(Acetyloxy)-4-ethoxybenzoic acid

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:224.06847348
Heavy Atom Count:16
Complexity:263

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC(=C(C=C1)C(=O)O)OC(=O)C

Technology Process of 2-(Acetyloxy)-4-ethoxybenzoic acid

There total 1 articles about 2-(Acetyloxy)-4-ethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 58138-64-0
2-Acetoxy-4-ethoxybenzoesaeure

Guidance literature:: 4-Ethoxysalicylsaeure, Ac2O;

Reference yield:

: 58138-64-0
2-Acetoxy-4-ethoxybenzoesaeure

: 58138-65-1
Acetic acid 2-chlorocarbonyl-5-ethoxy-phenyl ester

Guidance literature:: With oxalyl dichloride; In tetrahydrofuran; N,N-dimethyl-formamide; Ambient temperature;
DOI:10.1248/cpb.44.734

Reference yield:

: 58138-64-0
2-Acetoxy-4-ethoxybenzoesaeure

: N-(4-carbamimidoyl-phenyl)-4-ethoxy-2-hydroxy-benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: (COCl)2; DMF / ethyl acetate / 1 h

2: N,N-dimethyl-acetamide / 17 h

3: NH₄OH / tetrahydrofuran

With ammonium hydroxide; oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; N,N-dimethyl acetamide; ethyl acetate;
DOI:10.1016/S0960-894X(02)00312-8