Technology Process of N-Benzylpent-4-enethioamide
There total 1 articles about N-Benzylpent-4-enethioamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
n-butyllithium;
Yield given. Multistep reaction;
1.) THF, hexane, 0 deg C, 1 h, 2.) THF, -78 deg C to RT;
DOI:10.1016/S0040-4020(01)86180-9
- Guidance literature:
-
Multi-step reaction with 7 steps
1: K2CO3 / acetone / 15 h / Ambient temperature
2: iodine / tetrahydrofuran / 48 h / 5 °C
3: NaBH4, n-Bu3SnCl / ethanol / 1 h / 38 °C / Irradiation
4: 2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane-2,4-disulfide / benzene / 2 h / Heating
5: 1.) triethyloxonium boron tetrafluoride, 2.) NaBH4 / 1.) CH2Cl2, room temperature, 1 h, 2.) MeOH, room temperature, 1 h
6: 69 percent / hydrogen / Pd(OH)2 / methanol / 25 h
7: 99 percent / LiAlH4 / tetrahydrofuran / 15 h / Heating
With
Lawessons reagent; sodium tetrahydroborate; lithium aluminium tetrahydride; tributyltin chloride; hydrogen; iodine; triethyloxonium fluoroborate; potassium carbonate;
palladium dihydroxide;
In
tetrahydrofuran; methanol; ethanol; acetone; benzene;
DOI:10.1021/jo00281a022
- Guidance literature:
-
Multi-step reaction with 3 steps
1: K2CO3 / acetone / 15 h / Ambient temperature
2: iodine / tetrahydrofuran / 48 h / 5 °C
3: NaBH4, n-Bu3SnCl / ethanol / 1 h / 38 °C / Irradiation
With
sodium tetrahydroborate; tributyltin chloride; iodine; potassium carbonate;
In
tetrahydrofuran; ethanol; acetone;
DOI:10.1021/jo00281a022
