3-Hydroxy-4-methylpentanehydrazide

Base Information

• Chemical Name: 3-Hydroxy-4-methylpentanehydrazide
• CAS No.: 89582-40-1
• Molecular Formula: C₆H₁₄N₂O₂
• Molecular Weight: 146.189
• NSC Number: 171619
• DSSTox Substance ID: DTXSID80305762
• Mol file: 89582-40-1.mol

Synonyms:89582-40-1;3-hydroxy-4-methylpentanehydrazide;NSC171619;SCHEMBL22843767;DTXSID80305762;NSC-171619

Chemical Property of 3-Hydroxy-4-methylpentanehydrazide

Chemical Property:

• Vapor Pressure: 9.03E-06mmHg at 25°C
• Boiling Point: 334.4°Cat760mmHg
• Flash Point: 156°C
• Density: 1.079g/cm³
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 146.105527694
• Heavy Atom Count: 10
• Complexity: 114

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C(CC(=O)NN)O

Technology Process of 3-Hydroxy-4-methylpentanehydrazide

There total 4 articles about 3-Hydroxy-4-methylpentanehydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 3-hydroxy-4-methylpentanoate (65596-31-8) → 3-hydroxy-4-methylpentanehydrazide (89582-40-1)

Guidance literature:

With hydrazine hydrate; In ethanol; at 90 ℃; for 12h;

Reference yield:

ethyl 3-hydroxy-4-methylpentanoate (40309-42-0) → 3-hydroxy-4-methylpentanehydrazide (89582-40-1)

Guidance literature:

With hydrazine hydrate;

DOI:10.1246/bcsj.34.453

Reference yield:

ethyl 4-methyl-3-oxo-pentanoate (7152-15-0) → 3-hydroxy-4-methylpentanehydrazide (89582-40-1)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄

2: N₂H₄*H₂O

With sodium tetrahydroborate; hydrazine hydrate;

DOI:10.1246/bcsj.34.453

upstream raw materials:

ethyl 3-hydroxy-4-methylpentanoate

ethyl 4-methyl-3-oxo-pentanoate

Methyl 4-methyl-3-oxopentanoate

methyl 3-hydroxy-4-methylpentanoate

Refernces

• 1、 -. "BORON CONTAINING COMPOUNDS AND THEIR USES". . . Retrieved 2021/01/23.