2-Propen-1-one, 3-[4-(dimethylamino)phenyl]-1-(4-hydroxyphenyl)-

Base Information

• Chemical Name: 2-Propen-1-one, 3-[4-(dimethylamino)phenyl]-1-(4-hydroxyphenyl)-
• CAS No.: 5838-77-7
• Molecular Formula: C17H17NO2
• Molecular Weight: 267.327

Synonyms:4-Dimethylamino-4'-hydroxy-chalkon;3-(4-(dimethylamino)phenyl)-1-(4-hydroxyphenyl)prop-2-enone;(E)-3-(4-Dimethylamino-phenyl)-1-(4-hydroxy-phenyl)-propenone;3-(4-dimethylaminophenyl)-1-(4-hydroxyphenyl)-propenone;4-dimethylamino-4'-hydroxy-chalcone;3-(4-(dimethylamino)phenyl)-1-(4-hydroxyphenyl)prop-2-en-one;4-Oxy-ω-(4-dimethylamino-benzyliden)-acetophenon;

Chemical Property of 2-Propen-1-one, 3-[4-(dimethylamino)phenyl]-1-(4-hydroxyphenyl)-

Chemical Property:

• Melting Point: 84 - 88 °C
• PSA: 40.54000
• LogP: 3.35430

Purity/Quality:

95% ^*data from raw suppliers

3-[4-(DIMETHYLAMINO)PHENYL]-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propen-1-one, 3-[4-(dimethylamino)phenyl]-1-(4-hydroxyphenyl)-

There total 3 articles about 2-Propen-1-one, 3-[4-(dimethylamino)phenyl]-1-(4-hydroxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-dimethylamino-benzaldehyde (100-10-7) + 4-Hydroxyacetophenone (99-93-4) → 3-(4-(dimethylamino)phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one (5838-77-7)

Guidance literature:

With water; potassium hydroxide; at 20 ℃; for 0.5h;

Reference yield: 47.0%

4-hydroxyacetophenone + 4-dimethylamino-benzaldehyde (100-10-7) → 3-(4-(dimethylamino)phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one (5838-77-7)

Guidance literature:

With sodium hydroxide; In ethanol; at 0 - 20 ℃;

DOI:10.3390/molecules17066179

Reference yield:

→ 3-(4-(dimethylamino)phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one (5838-77-7)

Guidance literature:

4-Dimethylamino-benzaldehyd, 4-Hydroxy-acetophenon / A., 10percentig.wss.NaOH / 60grad / 3 h;

upstream raw materials:

4-dimethylamino-benzaldehyde

4-Hydroxyacetophenone

Downstream raw materials:

2-butyl-6-(5-(4-(dimethylamino)phenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

C₂₀H₁₈N₄O

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