2,6-Naphthyridin-1(2H)-one, 3,4-dihydro-

Base Information

Chemical Name:2,6-Naphthyridin-1(2H)-one, 3,4-dihydro-
CAS No.:58553-56-3
Molecular Formula:C₈H₈N₂O
Molecular Weight:148.164
Hs Code.:
Mol file:58553-56-3.mol

Synonyms:1,2,3,4-TETRAHYDRO-2,6-NAPHTHYRIDIN-1-ONE;3,4-dihydro-2H-[2,6]naphthyridin-1-one;3,4-dihydro-2,6-naphthyridin-1(2H)-one;Tetrahydro-2,6-naphthyridin-1-on;1,2,3,4-Tetrahydro-2,6-naphthyridin-1-on;

Suppliers and Price of 2,6-Naphthyridin-1(2H)-one, 3,4-dihydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
3,4-dihydro-2,6-Naphthyridin-1(2H)-one 97.00%
25G
$ 11400.00

AccelPharmtech
3,4-dihydro-2,6-Naphthyridin-1(2H)-one 97.00%
5G
$ 6050.00

AccelPharmtech
3,4-dihydro-2,6-Naphthyridin-1(2H)-one 97.00%
1G
$ 3510.00

Total 23 raw suppliers

Chemical Property of 2,6-Naphthyridin-1(2H)-one, 3,4-dihydro-

Chemical Property:

Melting Point:172-173 °C(Solv: ethanol (64-17-5))
Boiling Point:439.3±34.0 °C(Predicted)
PKA:13.05±0.20(Predicted)
PSA：41.99000
Density:1.214±0.06 g/cm3(Predicted)
LogP:0.69630

Purity/Quality:

97% ^*data from raw suppliers

3,4-dihydro-2,6-Naphthyridin-1(2H)-one 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,6-Naphthyridin-1(2H)-one, 3,4-dihydro-

There total 10 articles about 2,6-Naphthyridin-1(2H)-one, 3,4-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.1%

: 1365762-81-7
2-(4-methoxybenzyl)-3,4-dihydro-2,6-naphthyridin-1(2H)-one

: 58553-56-3
3,4-dihydro-2,6-naphthyridin-1(2H)-one

Guidance literature:: 2-(4-methoxybenzyl)-3,4-dihydro-2,6-naphthyridin-1(2H)-one; With toluene-4-sulfonic acid; In toluene; at 110 ℃; for 4h;

With hydrogenchloride; In water; pH=7;

Reference yield:

: 39931-77-6
pyridin-3-yl-acetic acid ethyl ester

: 58553-56-3
3,4-dihydro-2,6-naphthyridin-1(2H)-one

Guidance literature:: Multi-step reaction with 8 steps

1.1: 3-chloro-benzenecarboperoxoic acid / chloroform / 5 h / 20 °C / Inert atmosphere

1.2: pH 7

2.1: 144 h / 20 °C / Inert atmosphere

3.1: ethanol; water / 0.83 h / 50 °C

3.2: Cooling with ice

4.1: ethanol; sodium tetrahydroborate / 72 h / 20 °C

5.1: hydrogenchloride / water / 100 °C

6.1: tetrahydrofuran / Reflux

7.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran

8.1: toluene-4-sulfonic acid / toluene / 4 h / 110 °C

8.2: pH 7

With hydrogenchloride; sodium tetrahydroborate; ethanol; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; chloroform; water; toluene;

Reference yield:

: 3423-47-0
3-(2-ethoxy-2-oxoethyl)pyridin-1-ium-1-olate

: 58553-56-3
3,4-dihydro-2,6-naphthyridin-1(2H)-one

Guidance literature:: Multi-step reaction with 7 steps

1.1: 144 h / 20 °C / Inert atmosphere

2.1: ethanol; water / 0.83 h / 50 °C

2.2: Cooling with ice

3.1: ethanol; sodium tetrahydroborate / 72 h / 20 °C

4.1: hydrogenchloride / water / 100 °C

5.1: tetrahydrofuran / Reflux

6.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran

7.1: toluene-4-sulfonic acid / toluene / 4 h / 110 °C

7.2: pH 7

With hydrogenchloride; sodium tetrahydroborate; ethanol; toluene-4-sulfonic acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; water; toluene;