1-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)prop-2-en-1-one

Base Information

Chemical Name:1-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)prop-2-en-1-one
CAS No.:58759-45-8
Molecular Formula:C17H14N2O
Molecular Weight:262.311
Hs Code.:
DSSTox Substance ID:DTXSID30392384

Synonyms:1-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)prop-2-en-1-one;58759-45-8;DTXSID30392384

Suppliers and Price of 1-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)prop-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)prop-2-en-1-one

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:262.110613074
Heavy Atom Count:20
Complexity:371

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C=CC(=O)C2=NC3=CC=CC=C3N2

Technology Process of 1-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)prop-2-en-1-one

There total 3 articles about 1-(1H-benzimidazol-2-yl)-3-(4-methylphenyl)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 104-87-0
4-methyl-benzaldehyde

: 939-70-8
2-acetylbenzimidazole

: 58759-45-8
1-(1H-benzimidazol-2-yl)-3-(p-tolyl)-2-propen-1-one

Guidance literature:: With sodium hydroxide; at 20 ℃; for 0.333333h;

Reference yield:

: 16414-04-3,19018-24-7
1-benzimidazol-2-ylethanol

: 58759-45-8
1-(1H-benzimidazol-2-yl)-3-(p-tolyl)-2-propen-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / KMnO₄ on neutral alumina / 0.12 h / 20 °C

2: 89 percent / NaOH / 0.33 h / 20 °C

With sodium hydroxide; KMnO₄/alumina;

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 58759-45-8
1-(1H-benzimidazol-2-yl)-3-(p-tolyl)-2-propen-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / water / 6 h / Heating

2: potassium dichromate; sulfuric acid / 3 h / 20 °C

3: sodium hydroxide / ethanol / 12 h / 0 - 20 °C

With hydrogenchloride; potassium dichromate; sulfuric acid; sodium hydroxide; In ethanol; water; 3: |Claisen-Schmidt Condensation;
DOI:10.1007/s10593-015-1653-1