1-(3-Chlorophenyl)-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one

Base Information

Chemical Name:1-(3-Chlorophenyl)-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one
CAS No.:59361-47-6
Molecular Formula:C13H10ClN3O
Molecular Weight:259.695
Hs Code.:
DSSTox Substance ID:DTXSID60532594
Wikidata:Q82405315

Synonyms:59361-47-6;SCHEMBL5251844;1-(3-chlorophenyl)pyrido[2,3-d]pyrimidine-2(1H,3H)-one;DTXSID60532594;GUKZTMNMNAOZOX-UHFFFAOYSA-N;1-(3-Chlorophenyl)-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one;1-(m-chlorophenyl)-2-oxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine

Suppliers and Price of 1-(3-Chlorophenyl)-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1-(3-Chlorophenyl)-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one

Chemical Property:

PSA：48.72000
LogP:2.80130
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:259.0512396
Heavy Atom Count:18
Complexity:325

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(N=CC=C2)N(C(=O)N1)C3=CC(=CC=C3)Cl

Technology Process of 1-(3-Chlorophenyl)-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one

There total 2 articles about 1-(3-Chlorophenyl)-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 152815-09-3
2-(3-chloroanilino)-3-aminomethylpyridine

: 7732-18-5
water

: 530-62-1
1,1'-carbonyldiimidazole

: 59361-47-6
1-(m-chlorophenyl)-2-oxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine

Guidance literature:: In tetrahydrofuran; ethyl acetate;

Reference yield:

: 51085-24-6
2-(3-chloroanilino)-3-carbamoylpyridine

: 59361-47-6
1-(m-chlorophenyl)-2-oxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / tetrahydrofuran; ethyl acetate

2: tetrahydrofuran; ethyl acetate

With sodium hydroxide; In tetrahydrofuran; ethyl acetate;