N-Methyl-N-(5-phenyl-3H-1,4-benzodiazepin-2-yl)nitrous amide

Base Information

Chemical Name:N-Methyl-N-(5-phenyl-3H-1,4-benzodiazepin-2-yl)nitrous amide
CAS No.:59467-98-0
Molecular Formula:C16H14N4O
Molecular Weight:278.313
Hs Code.:
DSSTox Substance ID:DTXSID30516129
Nikkaji Number:J2.112.298J

Synonyms:59467-98-0;N-Methyl-N-(5-phenyl-3H-1,4-benzodiazepin-2-yl)nitrous amide;SCHEMBL7307922;DTXSID30516129

Suppliers and Price of N-Methyl-N-(5-phenyl-3H-1,4-benzodiazepin-2-yl)nitrous amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-Methyl-N-(5-phenyl-3H-1,4-benzodiazepin-2-yl)nitrous amide

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:278.11676108
Heavy Atom Count:21
Complexity:440

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C1=NC2=CC=CC=C2C(=NC1)C3=CC=CC=C3)N=O

Technology Process of N-Methyl-N-(5-phenyl-3H-1,4-benzodiazepin-2-yl)nitrous amide

There total 4 articles about N-Methyl-N-(5-phenyl-3H-1,4-benzodiazepin-2-yl)nitrous amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 34099-69-9
1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione

: 59467-98-0
2-(N-nitrosomethylamino)-5-phenyl-3H-1,4-benzodiazepine

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile; H₂O / 3 h / 20 °C

2: 0.33 g / sodium nitrite; AcOH / 3 h / 20 °C

With acetic acid; sodium nitrite; In water; acetonitrile;
DOI:10.1055/s-2004-831243

Reference yield:

: 59467-97-9
methyl-(5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-ylidene)-amine

: 59467-98-0
2-(N-nitrosomethylamino)-5-phenyl-3H-1,4-benzodiazepine

Guidance literature:: With acetic acid; sodium nitrite; at 20 ℃; for 3h;
DOI:10.1055/s-2004-831243

Reference yield:

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 59467-98-0
2-(N-nitrosomethylamino)-5-phenyl-3H-1,4-benzodiazepine

Guidance literature:: Multi-step reaction with 3 steps

1: P₂S₅; NaHCO₃ / acetonitrile / 24 h / Heating

2: acetonitrile; H₂O / 3 h / 20 °C

3: 0.33 g / sodium nitrite; AcOH / 3 h / 20 °C

With tetraphosphorus decasulfide; sodium hydrogencarbonate; acetic acid; sodium nitrite; In water; acetonitrile;
DOI:10.1055/s-2004-831243