{2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl}(2-fluorophenyl)methanone dihydrochloride

Base Information

Chemical Name:{2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl}(2-fluorophenyl)methanone dihydrochloride
CAS No.:59468-73-4
Molecular Formula:C18H15ClFN3O.2ClH
Molecular Weight:
Hs Code.:
European Community (EC) Number:611-832-4

Synonyms:59468-73-4;{2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl}(2-fluorophenyl)methanone dihydrochloride;SCHEMBL7313336;[2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl](2-fluorophenyl)-methanone Dihydrochloride;[2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl](2-fluorophenyl)-methanone Dihydrochloride (1mg/ml in Acetonitrile)

Suppliers and Price of {2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl}(2-fluorophenyl)methanone dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of {2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl}(2-fluorophenyl)methanone dihydrochloride

Chemical Property:

Vapor Pressure:4.37E-15mmHg at 25°C
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:415.042123
Heavy Atom Count:26
Complexity:452

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=NC=C(N1C2=C(C=C(C=C2)Cl)C(=O)C3=CC=CC=C3F)CN.Cl.Cl

Technology Process of {2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl}(2-fluorophenyl)methanone dihydrochloride

There total 10 articles about {2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl}(2-fluorophenyl)methanone dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59467-70-8
Midazolam

: 59468-73-4
5-aminomethyl-1-[4-chloro-2-(2-fluorobenzoyl)phenyl]-2-methyl-imidazole dihydrochloride

: 59467-96-8
midazolam hydrochloride

Guidance literature:: With hydrogenchloride; In water; at 20 ℃; for 8h;

Reference yield:

: 59467-70-8
Midazolam

: 59468-73-4
5-aminomethyl-1-[4-chloro-2-(2-fluorobenzoyl)phenyl]-2-methyl-imidazole dihydrochloride

Guidance literature:: With hydrogenchloride; In water;

Reference yield:

: 7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2-(1-nitromethylene)-2H-1,4-benzodiazepine 4-oxide

: 59468-73-4
5-aminomethyl-1-[4-chloro-2-(2-fluorobenzoyl)phenyl]-2-methyl-imidazole dihydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: aluminum nickel / tetrahydrofuran; methanol

2: PPA; acetic anhydride / methanol; dichloromethane; water

3: hydrogen / dichloromethane; water; acetic acid; Petroleum ether

4: manganese dioxide / toluene

5: hydrogenchloride / water

With hydrogenchloride; PPA; manganese dioxide; hydrogen; acetic anhydride; aluminum nickel; In tetrahydrofuran; methanol; dichloromethane; water; acetic acid; toluene; Petroleum ether;