4-[(2S)-2-aminopropyl]-N,N,3-trimethylaniline

Base Information

Chemical Name:4-[(2S)-2-aminopropyl]-N,N,3-trimethylaniline
CAS No.:77518-07-1
Deprecated CAS:77697-37-1
Molecular Formula:C₁₂H₂₀N₂
Molecular Weight:192.304
Hs Code.:
UNII:NE25WV9C8S
DSSTox Substance ID:DTXSID00228222
Nikkaji Number:J22.251H
Wikipedia:Amiflamine
Wikidata:Q4746184
NCI Thesaurus Code:C72695
ChEMBL ID:CHEMBL3989773
Mol file:77518-07-1.mol

Synonyms:4-dimethylamino-alpha,2-dimethylphenethylamine;amiflamin;amiflamin dihydrochloride;amiflamin, (+)-isomer;amiflamin, (-)-isomer;amiflamine;FLA 336;FLA 336(+);FLA-336

Suppliers and Price of 4-[(2S)-2-aminopropyl]-N,N,3-trimethylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4-[(2S)-2-aminopropyl]-N,N,3-trimethylaniline

Chemical Property:

Vapor Pressure:0.00051mmHg at 25°C
Refractive Index:1.553
Boiling Point:313°C at 760 mmHg
PKA:9.95±0.10(Predicted)
Flash Point:130.3°C
PSA：29.26000
Density:0.975g/cm³
LogP:2.65100
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:192.162648646
Heavy Atom Count:14
Complexity:168

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)N(C)C)CC(C)N
Isomeric SMILES:CC1=C(C=CC(=C1)N(C)C)C[C@H](C)N

Technology Process of 4-[(2S)-2-aminopropyl]-N,N,3-trimethylaniline

There total 2 articles about 4-[(2S)-2-aminopropyl]-N,N,3-trimethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 77502-96-6,77518-07-1,77518-08-2
4-(dimethylamino)-α,2-dimethylphenethylamine

Guidance literature:: entspr.β-Nitrostyrolderivat, LiAlH4;
DOI:10.1021/jm00199a010

Reference yield:

: 55875-42-8
4-dimethylamino-2,β-dimethyl-β-nitrostyrene

: 77518-07-1,77518-08-2
(+)-4-dimethylamino-2,β-dimethylphenethylamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; Yield given; Ambient temperature;

Reference yield:

: 1685-33-2
N-[(benzyloxy)carbonyl]-D-valine

: 77518-07-1,77518-08-2
(S)-amiflamine

: N-carbobenzyloxy-N'-(S)-<1-(4-dimethylamino-2-methylphenyl)-2-propyl>-(R)-valinamide

Guidance literature:: With 1,1'-carbonyldiimidazole; Yield given; Multistep reaction; 1) THF, reflux, 2) THF, reflux;
DOI:10.1016/S0223-5234(99)80047-6