5-[4-(Dimethylamino)phenyl]-1,3,4-oxadiazol-2-amine

Base Information

Chemical Name:5-[4-(Dimethylamino)phenyl]-1,3,4-oxadiazol-2-amine
CAS No.:59940-26-0
Molecular Formula:C10H12N4O
Molecular Weight:204.231
Hs Code.:
DSSTox Substance ID:DTXSID20406489
Wikidata:Q82211470

Synonyms:59940-26-0;5-[4-(Dimethylamino)phenyl]-1,3,4-oxadiazol-2-amine;5-(4-(Dimethylamino)phenyl)-1,3,4-oxadiazol-2-amine;SCHEMBL24653523;DTXSID20406489

Suppliers and Price of 5-[4-(Dimethylamino)phenyl]-1,3,4-oxadiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-[4-(DIMETHYLAMINO)PHENYL]-1,3,4-OXADIAZOL-2-AMINE 95.00%
5MG
$ 498.94

Total 0 raw suppliers

Chemical Property of 5-[4-(Dimethylamino)phenyl]-1,3,4-oxadiazol-2-amine

Chemical Property:

PSA：68.91000
LogP:1.31490
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:204.10111102
Heavy Atom Count:15
Complexity:204

Purity/Quality:: 5-[4-(DIMETHYLAMINO)PHENYL]-1,3,4-OXADIAZOL-2-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=CC=C(C=C1)C2=NN=C(O2)N

Technology Process of 5-[4-(Dimethylamino)phenyl]-1,3,4-oxadiazol-2-amine

There total 4 articles about 5-[4-(Dimethylamino)phenyl]-1,3,4-oxadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 2929-82-0
4-dimethylamino-benzaldehyde semicarbazone

: 59940-26-0
2-amino-5-(p-N,N-dimethylaminophenyl)-1,3,4-oxadiazole

Guidance literature:: With acetic acid; at 20 ℃; for 5h;

Reference yield: 70.0%

: p-(dimethylamino)benzamido-thiosemicarbazide

: 59940-26-0
2-amino-5-(p-N,N-dimethylaminophenyl)-1,3,4-oxadiazole

Guidance literature:: With Oxone; iodine; sodium hydroxide; In water; isopropyl alcohol; at 0 - 20 ℃; for 0.5h;
DOI:10.3184/174751912X13551638283701

Reference yield:

: 100-10-7
4-dimethylamino-benzaldehyde

: 59940-26-0
2-amino-5-(p-N,N-dimethylaminophenyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium acetate / water / 20 °C

2: bromine; sodium acetate / acetic acid / 0.5 h / 20 °C

With bromine; sodium acetate; In water; acetic acid;
DOI:10.1016/j.bmcl.2011.08.022