5(4H)-Oxazolone, 4-phenyl-2-(phenylmethyl)-

Base Information

Chemical Name:5(4H)-Oxazolone, 4-phenyl-2-(phenylmethyl)-
CAS No.:60050-57-9
Molecular Formula:C16H13NO2
Molecular Weight:251.285
Hs Code.:
DSSTox Substance ID:DTXSID60483971

Synonyms:60050-57-9;2-Benzyl-4-phenyloxazol-5(4H)-one;5(4H)-Oxazolone, 4-phenyl-2-(phenylmethyl)-;SCHEMBL4025767;DTXSID60483971

Suppliers and Price of 5(4H)-Oxazolone, 4-phenyl-2-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5(4H)-Oxazolone, 4-phenyl-2-(phenylmethyl)-

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:251.094628657
Heavy Atom Count:19
Complexity:352

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC2=NC(C(=O)O2)C3=CC=CC=C3

Technology Process of 5(4H)-Oxazolone, 4-phenyl-2-(phenylmethyl)-

There total 4 articles about 5(4H)-Oxazolone, 4-phenyl-2-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 35039-72-6,24003-71-2,24003-72-3
N-phenylacetyl-α-phenylglycine

: 60050-57-9
2-benzyl-4-phenyl-4H-oxazolin-5-one

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1055/s-2003-40196

Reference yield:

: phenyl-phenylacetylamino-acetic acid methyl ester

: 60050-57-9
2-benzyl-4-phenyl-4H-oxazolin-5-one

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / methanol

2: dicyclohexyl-carbodiimide / dichloromethane

With dicyclohexyl-carbodiimide; sodium hydroxide; In methanol; dichloromethane;
DOI:10.1021/jacs.5b10524

Reference yield:

: 24461-61-8,26682-99-5,37760-98-8,6591-61-3
phenylglycine methyl ester

: 60050-57-9
2-benzyl-4-phenyl-4H-oxazolin-5-one

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 0 - 20 °C

2: sodium hydroxide / methanol

3: dicyclohexyl-carbodiimide / dichloromethane

With triethylamine; dicyclohexyl-carbodiimide; sodium hydroxide; In methanol; dichloromethane;
DOI:10.1021/jacs.5b10524