2-Ethoxy-2-(methanesulfonyl)-1-phenylethan-1-one

Base Information

• Chemical Name: 2-Ethoxy-2-(methanesulfonyl)-1-phenylethan-1-one
• CAS No.: 60279-04-1
• Molecular Formula: C₁₁H₁₄O₄S
• Molecular Weight: 242.296
• DSSTox Substance ID: DTXSID80492166
• Mol file: 60279-04-1.mol

Synonyms:60279-04-1;2-Ethoxy-2-(methanesulfonyl)-1-phenylethan-1-one;DTXSID80492166

Chemical Property of 2-Ethoxy-2-(methanesulfonyl)-1-phenylethan-1-one

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 242.06128010
• Heavy Atom Count: 16
• Complexity: 322

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(C(=O)C1=CC=CC=C1)S(=O)(=O)C

Technology Process of 2-Ethoxy-2-(methanesulfonyl)-1-phenylethan-1-one

There total 1 articles about 2-Ethoxy-2-(methanesulfonyl)-1-phenylethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylsulfonyl-1-phenylethanone (3708-04-1) → 2-ethoxy-2-methanesulfonyl-1-phenyl-ethanone (60279-04-1)

Guidance literature:

Multi-step reaction with 2 steps

1: TsN₃, Et₃N / ethanol

2: aq. HClO₄, Cu

With perchloric acid; 4-toluenesulfonyl azide; copper; triethylamine; In ethanol;

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-ethoxy-2-methanesulfonyl-1-phenyl-ethanone (60279-04-1) → α-Ethoxy-zimtaldehyd (60279-03-0)

Guidance literature:

Multistep reaction; (i) NaH, MeCN, (ii) /BRN= 1209228/;

DOI:10.1055/s-1976-24060

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-ethoxy-2-methanesulfonyl-1-phenyl-ethanone (60279-04-1) → 2-ethoxy-1-phenyl-2-propen-1-one (85616-23-5)

Guidance literature:

Multistep reaction; (i) NaH, MeCN, (ii) /BRN= 1209228/;

DOI:10.1055/s-1976-24060

upstream raw materials:

2-methylsulfonyl-1-phenylethanone

Downstream raw materials:

α-Ethoxy-zimtaldehyd

2-ethoxy-1-phenyl-2-propen-1-one