Benzenethiol, 2-(aminomethyl)-

Base Information

• Chemical Name: Benzenethiol, 2-(aminomethyl)-
• CAS No.: 6047-42-3
• Molecular Formula: C7H9NS
• Molecular Weight: 139.221
• Mol file: 6047-42-3.mol

Synonyms:

Chemical Property of Benzenethiol, 2-(aminomethyl)-

Chemical Property:

• Boiling Point: 256.6±15.0 °C(Predicted)
• Density: 1.140±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenethiol, 2-(aminomethyl)-

There total 5 articles about Benzenethiol, 2-(aminomethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-allylsulfanyl-benzylamine (199437-83-7) → 2-aminomethyl-benzenethiol (6047-42-3)

Guidance literature:

With carbon monoxide; hydrogen; triphenylphosphine; dirhodium tetraacetate; In ethyl acetate; at 80 ℃; for 20h; under 20685.9 Torr; Yield given;

DOI:10.1071/C97057

Reference yield:

o-nitrobenzonitrile (612-24-8) → 2-aminomethyl-benzenethiol (6047-42-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 79 percent / KOH / H₂O / 0.5 h / 0 °C

2: 90 percent / LiAlH₄ / diethyl ether / 5 h / Heating

3: CO, H₂, Ph₃P / rhodium(II) acetate dimer / ethyl acetate / 20 h / 80 °C / 20685.9 Torr

With potassium hydroxide; lithium aluminium tetrahydride; carbon monoxide; hydrogen; triphenylphosphine; dirhodium tetraacetate; In diethyl ether; water; ethyl acetate;

DOI:10.1071/C97057

Reference yield:

2-(prop-2'-enylthio)benzonitrile (199437-80-4) → 2-aminomethyl-benzenethiol (6047-42-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / LiAlH₄ / diethyl ether / 5 h / Heating

2: CO, H₂, Ph₃P / rhodium(II) acetate dimer / ethyl acetate / 20 h / 80 °C / 20685.9 Torr

With lithium aluminium tetrahydride; carbon monoxide; hydrogen; triphenylphosphine; dirhodium tetraacetate; In diethyl ether; ethyl acetate;

DOI:10.1071/C97057

upstream raw materials:

2-allylsulfanyl-benzylamine

2-methanesulfinyl-benzonitrile

o-nitrobenzonitrile

2-(prop-2'-enylthio)benzonitrile

Downstream raw materials:

2-Benzoyl-4H-1,3-benzothiazine