5-(2-Cyclohexylpropan-2-yl)benzene-1,3-diol

Base Information

Chemical Name:5-(2-Cyclohexylpropan-2-yl)benzene-1,3-diol
CAS No.:60526-88-7
Molecular Formula:C15H22O2
Molecular Weight:234.33400
Hs Code.:
DSSTox Substance ID:DTXSID00488602
Wikidata:Q82331369

Synonyms:5-(2-Cyclohexylpropan-2-yl)benzene-1,3-diol;60526-88-7;5-(1-Cyclohexyl-1-methyl-ethyl)-benzene-1,3-diol;SCHEMBL1039185;DTXSID00488602;KJSPFEUPTUMFIR-UHFFFAOYSA-N

Suppliers and Price of 5-(2-Cyclohexylpropan-2-yl)benzene-1,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(2-Cyclohexylpropan-2-yl)benzene-1,3-diol

Chemical Property:

PSA：40.46000
LogP:3.95570
XLogP3:5.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:234.161979940
Heavy Atom Count:17
Complexity:233

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C1CCCCC1)C2=CC(=CC(=C2)O)O

Technology Process of 5-(2-Cyclohexylpropan-2-yl)benzene-1,3-diol

There total 5 articles about 5-(2-Cyclohexylpropan-2-yl)benzene-1,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.9%

: 60526-83-2
1-(1-cyclohexyl-1-methyl-ethyl)-3,5-dimethoxy-benzene

: 60526-88-7
5-(1-cyclohexyl-1-methyl-ethyl)-benzene-1,3-diol

Guidance literature:: With boron tribromide; In dichloromethane; at 0 ℃;
DOI:10.1016/S0968-0896(03)00238-4

Reference yield: 61.9%

: 60526-88-7
5-(1-cyclohexyl-1-methyl-ethyl)-benzene-1,3-diol

Guidance literature:

Reference yield:

: 108-85-0
1-bromocyclohexane

: 60526-88-7
5-(1-cyclohexyl-1-methyl-ethyl)-benzene-1,3-diol

Guidance literature:: Multi-step reaction with 3 steps

1.1: Mg / tetrahydrofuran / Heating

1.2: tetrahydrofuran / 3 h / Heating

1.3: 63.3 percent / aq. HCl / tetrahydrofuran / Heating

2.1: TiCl₄ / CH₂Cl₂; toluene

2.2: 70.3 percent / CH₂Cl₂; toluene

3.1: 61.9 percent / BBr₃ / CH₂Cl₂ / 0 °C

With boron tribromide; titanium tetrachloride; magnesium; In tetrahydrofuran; dichloromethane; toluene; 1.2: Grignard reaction;
DOI:10.1016/S0968-0896(03)00238-4