4-Quinolinecarboxylic acid, 2-(2-carboxyphenyl)-

Base Information

• Chemical Name: 4-Quinolinecarboxylic acid, 2-(2-carboxyphenyl)-
• CAS No.: 60539-01-7
• Molecular Formula: C17H11NO4
• Molecular Weight: 293.279
• Mol file: 60539-01-7.mol

Synonyms:

Chemical Property of 4-Quinolinecarboxylic acid, 2-(2-carboxyphenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Quinolinecarboxylic acid, 2-(2-carboxyphenyl)-

There total 1 articles about 4-Quinolinecarboxylic acid, 2-(2-carboxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetyl-benzoic acid (577-56-0) + indole-2,3-dione (91-56-5,1186480-61-4,84788-92-1) → 2-(2-Carboxyphenyl)-4-quinoline carboxylic acid (60539-01-7)

Guidance literature:

With potassium hydroxide;

Reference yield:

2-(2-Carboxyphenyl)-4-quinoline carboxylic acid (60539-01-7) → 2-[2]quinolyl-benzoic acid (170954-08-2)

Guidance literature:

With sulfuric acid; sodium carbonate; In quinoline;

Reference yield:

2-(2-Carboxyphenyl)-4-quinoline carboxylic acid (60539-01-7) → 2-(4-hydroxy-[2]quinolyl)-benzoic acid

Guidance literature:

Multi-step reaction with 4 steps

1: sodium-amalgam; aqueous Na₂CO₃

2: water; acetic acid; chromium (VI)-oxide

3: selenium dioxide; xylene

4: methanol. KOH

With chromium(VI) oxide; potassium hydroxide; sodium amalgam; selenium(IV) oxide; water; sodium carbonate; acetic acid; xylene;

DOI:10.1002/hlca.19430260616

upstream raw materials:

2-acetyl-benzoic acid

indole-2,3-dione

Downstream raw materials:

2-[2]quinolyl-benzoic acid

Refernces

• 1、 -. "Process for producing quinolin-2-yl benzoic acid compounds". . . Retrieved 2008/06/13.