2-Amino-4-(benzyloxy)-5-methoxybenzamide

Base Information

Chemical Name:2-Amino-4-(benzyloxy)-5-methoxybenzamide
CAS No.:60547-98-0
Molecular Formula:C15H16N2O3
Molecular Weight:272.304
Hs Code.:
European Community (EC) Number:865-827-9
DSSTox Substance ID:DTXSID50499566
Wikidata:Q82350450

Synonyms:60547-98-0;2-amino-4-benzyloxy-5-methoxybenzamide;2-AMINO-4-(BENZYLOXY)-5-METHOXYBENZAMIDE;2-amino-5-methoxy-4-phenylmethoxybenzamide;SCHEMBL159448;DTXSID50499566;DNPHXICYCDCOAR-UHFFFAOYSA-N;E83373;EN300-25185645;Z2050103912

Suppliers and Price of 2-Amino-4-(benzyloxy)-5-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Amino-4-(benzyloxy)-5-methoxybenzamide

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:272.11609238
Heavy Atom Count:20
Complexity:318

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C(=C1)C(=O)N)N)OCC2=CC=CC=C2

Technology Process of 2-Amino-4-(benzyloxy)-5-methoxybenzamide

There total 8 articles about 2-Amino-4-(benzyloxy)-5-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 385784-84-9
4-(benzyloxy)-5-methoxy-2-nitrobenzonitrile

: 60547-98-0
2-amino-4-benzyloxy-5-methoxybenzamide

Guidance literature:: With iron; ammonium chloride; In water; isopropyl alcohol; for 4h; Reflux;

Reference yield:

: 2426-87-1
3-methoxy-4-(phenylmethoxy)benzaldehyde

: 60547-98-0
2-amino-4-benzyloxy-5-methoxybenzamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: nitric acid / 2 h / 0 - 20 °C

2.1: potassium permanganate / acetone / 2 h / 30 - 50 °C

3.1: oxalyl dichloride / toluene / 2 h / Reflux

3.2: 2 h

4.1: acetic acid / 0.17 h / 90 °C

4.2: 1 h / Reflux

With potassium permanganate; oxalyl dichloride; nitric acid; acetic acid; In acetone; toluene;

Reference yield:

: 2426-84-8
4-(benzyloxy)-5-methoxy-2-nitrobenzaldehyde

: 60547-98-0
2-amino-4-benzyloxy-5-methoxybenzamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium permanganate / acetone / 2 h / 30 - 50 °C

2.1: oxalyl dichloride / toluene / 2 h / Reflux

2.2: 2 h

3.1: acetic acid / 0.17 h / 90 °C

3.2: 1 h / Reflux

With potassium permanganate; oxalyl dichloride; acetic acid; In acetone; toluene;