Cyclohexanol, 3-phenyl-3-(1-piperidinyl)-

Base Information

• Chemical Name: Cyclohexanol, 3-phenyl-3-(1-piperidinyl)-
• CAS No.: 60756-95-8
• Molecular Formula: C₁₇H₂₅NO
• Molecular Weight: 259.392

Synonyms:

Chemical Property of Cyclohexanol, 3-phenyl-3-(1-piperidinyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexanol, 3-phenyl-3-(1-piperidinyl)-

There total 10 articles about Cyclohexanol, 3-phenyl-3-(1-piperidinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hydroxycyclohexanone (823-19-8) → 3-phenyl-3-(1-piperidinyl)cyclohexanol (60756-95-8,80770-77-0,80770-78-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 8.3 g

2: NaN₃, CCl₃COOH / CHCl₃ / 5 h / 0 °C

3: LiAlH₄ / diethyl ether / Heating

4: 0.7 g / K₂CO₃ / acetone / 96 h / Heating

With lithium aluminium tetrahydride; sodium azide; potassium carbonate; trichloroacetic acid; In diethyl ether; chloroform; acetone;

DOI:10.1021/jm00346a019

Reference yield:

3-hydroxycyclohexanone (823-19-8) → 3-phenyl-3-(1-piperidinyl)cyclohexanol (60756-95-8,80770-77-0,80770-78-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 8.3 g

2: NaN₃, CCl₃COOH / CHCl₃ / 5 h / 0 °C

3: LiAlH₄ / diethyl ether / Heating

4: 1 g / K₂CO₃ / acetone / 96 h / Heating

With lithium aluminium tetrahydride; sodium azide; potassium carbonate; trichloroacetic acid; In diethyl ether; chloroform; acetone;

DOI:10.1021/jm00346a019

Reference yield:

phenylmagnesium bromide → 3-phenyl-3-(1-piperidinyl)cyclohexanol (60756-95-8,80770-77-0,80770-78-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 8.3 g

2: NaN₃, CCl₃COOH / CHCl₃ / 5 h / 0 °C

3: LiAlH₄ / diethyl ether / Heating

4: 0.7 g / K₂CO₃ / acetone / 96 h / Heating

With lithium aluminium tetrahydride; sodium azide; potassium carbonate; trichloroacetic acid; In diethyl ether; chloroform; acetone;

DOI:10.1021/jm00346a019

upstream raw materials:

1,5-dibromo-pentane

3-hydroxycyclohexanone

1-phenyl-3-hydroxycyclohexanol

Refernces

Mass spectra of stereoisomers of 3-piperidinocyclohexanol derivatives

10.1248/cpb.38.23

The research aimed to investigate the mass spectra of stereoisomers of 3-piperidinocyclohexanol derivatives. The study's purpose was to distinguish between cis- and trans-configurations of these derivatives and to recognize the difference between alkyl and phenyl substituents through peak intensities in mass spectrometry. The researchers used electron impact ionization to measure the mass spectra of compounds 1-6, which included various alkyl and phenyl derivatives of 3-piperidinocyclohexanol. The conclusions drawn from the study were that the cis- and trans-isomers could be differentiated by the peak intensities at m/z 140 and m/z 85, and the distinction between alkyl and phenyl derivatives was possible by observing the peak intensities at m/z 182 and m/z 164. The research provided valuable insights into the stereospecific effects in mass spectrometry and could aid in configurational assignment in analogous systems.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 60756-95-8 Cyclohexanol, 3-phenyl-3-(1-piperidinyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send