7-methoxy-2H-phthalazin-1-one

Base Information

Chemical Name:7-methoxy-2H-phthalazin-1-one
CAS No.:60889-22-7
Molecular Formula:C₉H₈N₂O₂
Molecular Weight:176.175
Hs Code.:
DSSTox Substance ID:DTXSID70486039
Wikidata:Q82325952

Synonyms:60889-22-7;7-methoxy-2H-phthalazin-1-one;7-Methoxyphthalazin-1(2H)-one;SCHEMBL1526819;7-methoxy-1(2H)-phthalazinone;DTXSID70486039;YIZCCTNPTLWTFJ-UHFFFAOYSA-N;AT14865;EN300-339562

Suppliers and Price of 7-methoxy-2H-phthalazin-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
7-Methoxy-2H-phthalazin-1-one
10g
$ 4075.00

AK Scientific
7-Methoxy-2H-phthalazin-1-one
1g
$ 1024.00

AK Scientific
7-Methoxy-2H-phthalazin-1-one
250mg
$ 556.00

Total 2 raw suppliers

Chemical Property of 7-methoxy-2H-phthalazin-1-one

Chemical Property:

PSA：55.24000
LogP:1.34400
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:176.058577502
Heavy Atom Count:13
Complexity:240

Purity/Quality:

97% ^*data from raw suppliers

7-Methoxy-2H-phthalazin-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C=NNC2=O

Technology Process of 7-methoxy-2H-phthalazin-1-one

There total 6 articles about 7-methoxy-2H-phthalazin-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 4785-56-2
2-formyl-5-methoxy-benzoic acid

: 60889-22-7
7-methoxyphthalazin-1-(2H)-one

Guidance literature:: With hydrazine; In ethanol; at 70 - 80 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.joc.5b02652

Reference yield: 25.0%

: 60889-22-7
7-methoxyphthalazin-1-(2H)-one

Guidance literature:

Reference yield:

: 4741-63-3
6-methoxyphthalide

: 60889-22-7
7-methoxyphthalazin-1-(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 3 h / Reflux

2: hydrazine hydrate / ethanol / 14 h / Reflux

With N-Bromosuccinimide; hydrazine hydrate; dibenzoyl peroxide; In tetrachloromethane; ethanol;
DOI:10.1039/c6ra03841g