2,3,5,7-Tetrahydroxy-1,4-naphthoquinone

Base Information

• Chemical Name: 2,3,5,7-Tetrahydroxy-1,4-naphthoquinone
• CAS No.: 604-46-6
• Molecular Formula: C₁₀H₆O₆
• Molecular Weight: 222.154
• Mol file: 604-46-6.mol

Synonyms:1,4-Naphthoquinone,2,3,5,7-tetrahydroxy- (6CI,7CI,8CI);2,3,5,7-Tetrahydroxy-1,4-naphthoquinone;NSC 288042;Spinochrom B;2,3,5,7-tetrahydroxynaphthalene-1,4-dione;

Chemical Property of 2,3,5,7-Tetrahydroxy-1,4-naphthoquinone

Chemical Property:

• Vapor Pressure: 2.15E-06mmHg at 25°C
• Refractive Index: 1.811
• Boiling Point: 499.5 °C at 760 mmHg
• Flash Point: 270 °C
• PSA: 115.06000
• Density: 2.031 g/cm³
• LogP: 0.80440

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,5,7-Tetrahydroxy-1,4-naphthoquinone

There total 4 articles about 2,3,5,7-Tetrahydroxy-1,4-naphthoquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-Dihydroxy-5,7-dimethoxy-<1,4>naphthochinon (853647-65-1) → 2,3,5,7-tetrahydroxy-1,4-naphthoquinone (604-46-6)

Guidance literature:

With aluminium trichloride; sodium chloride; at 180 ℃;

DOI:10.1039/jr9610001008

Reference yield:

2,3-epoxy-5,7-dimethoxy-2,3-dihydro-[1,4]naphthoquinone (108171-21-7) → 2,3,5,7-tetrahydroxy-1,4-naphthoquinone (604-46-6)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂SO₄

2: aq. NaOH

3: AlCl₃, NaCl / 180 °C

With sodium hydroxide; aluminium trichloride; sulfuric acid; sodium chloride;

DOI:10.1039/jr9610001008

Reference yield:

5,7-Dimethoxy-2,3-diacetoxy-1,4-dioxo-1,2,3,4-tetrahydro-naphthalin (131866-55-2) → 2,3,5,7-tetrahydroxy-1,4-naphthoquinone (604-46-6)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH

2: AlCl₃, NaCl / 180 °C

With sodium hydroxide; aluminium trichloride; sodium chloride;

DOI:10.1039/jr9610001008

upstream raw materials:

2,3-Dihydroxy-5,7-dimethoxy-<1,4>naphthochinon

2,3-epoxy-5,7-dimethoxy-2,3-dihydro-[1,4]naphthoquinone

5,7-Dimethoxy-2,3-diacetoxy-1,4-dioxo-1,2,3,4-tetrahydro-naphthalin

Downstream raw materials:

3,5-dimethoxyphthalic acid